48 citations · 180 across the 6 of their papers we have counts for
6 papers
Anharmonicity and self-similarity of the free energy landscape of protein G
F. Pontiggia, G. Colombo, C. Micheletti +1
The near-native free energy landscape of protein G is investigated through 0.4 microseconds-long atomistic molecular dynamics simulations in explicit solvent. A theoretical and com…
Conformations of Proteins in Equilibrium
Cristian Micheletti, Jayanth Banavar, Amos Maritan
We introduce a simple theoretical approach for an equilibrium study of proteins with known native state structures. We test our approach with results on well-studied globular prote…
Recurrent oligomers in proteins - an optimal scheme reconciling accurate and concise backbone representations in automated folding and design studies
Cristian Micheletti, Flavio Seno, Amos Maritan
A novel scheme is introduced to capture the spatial correlations of consecutive amino acids in naturally occurring proteins. This knowledge-based strategy is able to carry out opti…
Role of Secondary Motifs in Fast Folding Polymers: A Dynamical Variational Principle
Amos Maritan, Cristian Micheletti, Jayanth R. Banavar
A fascinating and open question challenging biochemistry, physics and even geometry is the presence of highly regular motifs such as alpha-helices in the folded state of biopolymer…
A novel iterative strategy for protein design
A. Rossi, A. Maritan, C. Micheletti
We propose and discuss a novel strategy for protein design. The method is based on recent theoretical advancements which showed the importance to treat carefully the conformational…
Protein design in a lattice model of hydrophobic and polar amino acids
C. Micheletti, F. Seno, A. Maritan +1
A general strategy is described for finding which amino acid sequences have native states in a desired conformation (inverse design). The approach is used to design sequences of 48…