65 citations · 265 across the 17 of their papers we have counts for
18 papers
Mechanistic Insights into Chemical Exchange during the Signal Amplification by Reversible Exchange Sensitization of Pyruvate
Charbel D. Assaf, Vladimir V. Zhivonitko, Amaia Vicario +4
Signal amplification by reversible exchange (SABRE) is a nuclear spin hyperpolarization technique in which the transient interaction of parahydrogen (pH2) and a target substrate wi…
Over four minutes relaxation of pyruvate using chemically and physically induced deceleration of relaxation
Josh P. Peters, Florin Teleanu, Huijing Zou +4
[1-13C]pyruvate is the most widely used tracer for hyperpolarized metabolic magnetic resonance imaging, with profound applications in tumor and inflammation diagnosis as well as tr…
Upscaling the hyperpolarization sample volume of an automated hydrogenative parahydrogen-induced polarizer
Yenal Gökpek, Jan-Bernd Hövener, Andrey N. Pravdivtsev
Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) suffer from inherently low sensitivity due to the weak thermal polarization of nuclear spins. Parahydrogen-ind…
Compact magnetic field cycling system with the range from nT to 9.4 T exemplified with 13C relaxation dispersion and SABRE-SHEATH hyperpolarization
Josh P. Peters, Charbel D. Assaf, Jan-Bernd Hövener +1
We present a compact magnetic field cycling system for high-resolution NMR spectrometers. The system enables the transfer of the sample from B0 field of 9.4 T to about nT and all f…
Indirect Zero Field NMR Spectroscopy
Kai Buckenmaier, Richard Neumann, Friedemann Bullinger +11
This study pioneers the two-field correlation spectroscopy (COSY) in zero to ultralow field (ZULF) liquid state NMR, employing hyperpolarized [1-C]pyruvate as a model system…
Diversity of Parahydrogen-Induced Hyperpolarization Effects in Chemistry
Andrey N. Pravdivtsev, Ben. J. Tickner, Stefan Glöggler +5
Nuclear spin hyperpolarization utilizing parahydrogen has the potential for broad applications in chemistry, biochemistry, and medicine. This review examines recent chemical and bi…
Characterization of Nuclear Magnetism at Ultralow and Zero Field using SQUIDs
John Z. Myers, Kai Buckenmaier, Andrey N. Pravdivtsev +2
Nuclear magnetism underpins areas such as medicine in magnetic resonance imaging (MRI). Hyperpolarization of nuclei enhances the quantity and quality of information that can be det…
Maximizing NMR Sensitivity: A Guide to Receiver Gain Adjustment
Josh P. Peters, Frank D. Sönnichsen, Jan-Bernd Hövener +1
Novel methods and technology drive the rapid advances of nuclear magnetic resonance (NMR). The primary objective of developing novel hardware is to improve sensitivity and reliabil…
Magnetization and Polarization of Coupled Nuclear Spin Ensembles
Danila A. Barskiy, Andrey Pravdivtsev
In nuclear magnetic resonance (NMR), the bulk magnetization of a sample is commonly assumed to be proportional to spin polarization, with each spin of the same type contributing eq…
LIGHT-SABRE hyperpolarizes 1-^{13}C-pyruvate continuously, without magnetic field cycling
Andrey N. Pravdivtsev, Kai Buckenmaier, Nicolas Kempf +7
Nuclear spin hyperpolarization enables real-time observation of metabolism and intermolecular interactions in vivo. 1-13C-Pyruvate is the leading hyperpolarized tracer currently un…
Symmetry constraints on spin order transfer in parahydrogen-induced polarization (PHIP)
Andrey N. Pravdivtsev, Danila A. Barskiy, Jan-Bernd Hövener +1
It is well known that the association of parahydrogen (pH2) with an unsaturated molecule or a transient metalorganic complex can enhance the intensity of NMR signals; the effect is…
Selectively pulsed spin order transfer increases parahydrogen-induced NMR amplification of insensitive nuclei and makes polarization transfer more robust
Andreas B. Schmidt, Arne Brahms, Frowin Ellermann +6
We describe a new method for pulsed spin order transfer (SOT) of parahydrogen induced polarization (PHIP) that enables close to 100 % polarization in incompletely 2H-labeled molecu…
Coherent evolution of signal amplification by reversible exchange in two alternating fields (alt-SABRE)
Andrey N. Pravdivtsev, Nicolas Kempf, Markus Plaumann +4
Parahydrogen (pH2) is a convenient and cost efficient source for magnetic resonance signal enhancement. Transient interaction of pH2 with a metal organic complex in a signal amplif…
Parahydrogen-induced polarization relayed via proton exchange
Kolja Them, Frowin Ellermann, Andrey N. Pravdivtsev +5
The sensitivity of NMR and MRI can be boosted via hyperpolarization of nuclear spins. However, current methods are costly, polarization is relatively low, or applicability is limit…
Singlet state encoded magnetic resonance (SISTEM) spectroscopy
Andrey N. Pravdivtsev, Frank D. Sönnichsen, Jan-Bernd Hövener
Magnetic resonance spectroscopy (MRS) allows the analysis of biochemical processes non invasively and in vivo. Still, its application in clinical diagnostics is rare. Routine MRS i…
Continuous Radio Amplification by Stimulated Emission using Parahydrogen Induced Polarization (PHIP-RASER) at 14 Tesla
Andrey N. Pravdivtsev, Frank D. Sönnichsen, Jan-Bernd Hövener
Nuclear Magnetic Resonance (NMR) is an intriguing quantum-mechanical effect that is used for daily life medical diagnostics and chemical analysis alike. Numerous advancements have…
Simultaneous observation of high order multiple quantum coherences at ultralow magnetic fields
K. Buckenmaier, K. Scheffler, M. Plaumann +8
We present a method for the simultaneous observation of heteronuclear multi-quantum coherences (up to the 3rd order), which give an additional degree of freedom for ultralow magnet…
Robust conversion of singlet spin order in coupled spin-1/2 pairs by adiabatically switched RF-fields
Andrey N. Pravdivtsev, Alexey S. Kiryutin, Alexandra V. Yurkovskaya +2
We propose a robust and highly efficient NMR technique to create singlet spin order from longitudinal spin magnetization in coupled spin-1/2 pairs and to perform backward conversio…