activity
20182021
most citedBubble lifetimes in DNA gene promoters and their mutations affecting transcription

16 citations · 16 across the 2 of their papers we have counts for

collaborators

6 papers

q-bio.BM202116 cited

Bubble lifetimes in DNA gene promoters and their mutations affecting transcription

M Hillebrand, G Kalosakas, A R Bishop +1

Relative lifetimes of inherent double stranded DNA openings with lengths up to ten base pairs are presented for different gene promoters and corresponding mutants that either incre…

nlin.CD2021

Chaotic Dynamics of Polyatomic Systems with an Emphasis on DNA Models

Malcolm Hillebrand

We investigate the chaotic behaviour of multiparticle systems, in particular DNA and graphene models, by applying methods of nonlinear dynamics. Using symplectic integration techni…

physics.bio-ph2020

Distributions of Bubble Lifetimes and Bubble Lengths in DNA

Malcolm Hillebrand, George Kalosakas, Haris Skokos +1

We investigate the distribution of bubble lifetimes and bubble lengths in DNA at physiological temperature, by performing extensive molecular dynamics simulations with the Peyrard-…

nlin.CD2020

Chaotic dynamics of graphene and graphene nanoribbons

Malcolm Hillebrand, Bertin Many Manda, George Kalosakas +2

We study the chaotic dynamics of graphene structures, considering both a periodic, defect free, graphene sheet and graphene nanoribbons (GNRs) of various widths. By numerically cal…

nlin.CD2018

Heterogeneity and chaos in the Peyrard-Bishop-Dauxois DNA model

Malcolm Hillebrand, George Kalosakas, Adrian Schwellnus +1

We discuss the effect of heterogeneity on the chaotic properties of the Peyrard-Bishop-Dauxois nonlinear model of DNA. Results are presented for the maximum Lyapunov exponent and t…

math.CO2018

Distribution of Base Pair Alternations in a Periodic DNA Chain: Application of Polya Counting to a Physical System

Malcolm Hillebrand, Guy Paterson-Jones, George Kalosakas +1

In modeling DNA chains, the number of alternations between Adenine-Thymine (AT) and Guanine-Cytosine (GC) base pairs can be considered as a measure of the heterogeneity of the chai…