3 papers
cs.LG2024
deepNoC: A deep learning system to assign the number of contributors to a short tandem repeat DNA profile
Duncan Taylor, Melissa A. Humphries
A common task in forensic biology is to interpret and evaluate short tandem repeat DNA profiles. The first step in these interpretations is to assign a number of contributors to th…
q-bio.QM2024
A novel application of Shapley values for large multidimensional time-series data: Applying explainable AI to a DNA profile classification neural network
Lauren Elborough, Duncan Taylor, Melissa Humphries
The application of Shapley values to high-dimensional, time-series-like data is computationally challenging - and sometimes impossible. For inputs the problem is hard. In…
cs.LG2024
Simulating realistic short tandem repeat capillary electrophoretic signal using a generative adversarial network
Duncan Taylor, Melissa Humphries
DNA profiles are made up from multiple series of electrophoretic signal measuring fluorescence over time. Typically, human DNA analysts 'read' DNA profiles using their experience t…