9 papers
PVS-Facing AQP4 Transport and Dynamic Inter-Endfoot Gaps Regulate Gap-Dominated Glymphatic Clearance: Implications for Aging
Tanran Zhang, Shixin Xu
Experimental studies show that impaired aquaporin-4 (AQP4) function or polarization reduces glymphatic clearance, whereas recent mechanical models suggest that pressure-driven wate…
A novel multiscale modelling for the hemodynamics in retinal microcirculation with an analytic solution for the capillary-tissue coupled system
Chang Lin, Zilong Song, Robert Eisenberg +2
Mathematical modelling of the microcirculatory hemodynamics in the retina is an essential tool for understanding various diseases of the retina, yet remains challenging due to the…
TWLR: Text-Guided Weakly-Supervised Lesion Localization and Severity Regression for Explainable Diabetic Retinopathy Grading
Xi Luo, Shixin Xu, Ying Xie +4
Accurate medical image analysis can greatly assist clinical diagnosis, but its effectiveness relies on high-quality expert annotations Obtaining pixel-level labels for medical imag…
Glymphatic Clearance in the Optic Nerve: A Multidomain Electro-osmostic Model
Shanfeng Xiao, Huaxiong Huang, Robert Eisenberg +2
Effective metabolic waste clearance and maintaining ionic homeostasis are essential for the health and normal function of the central nervous system. To understand its mechanism an…
Pump-driven droplet electrohydrodynamics: deformation, pinch-off and recoalescence
Yuzhe Qin, Huaxiong Huang, Zilong Song +1
We investigate pump-driven droplet electrohydrodynamics with an emphasis on deformation, pinch-off, and recoalescence. A thermodynamically consistent phase-field framework is devel…
Beyond Single-Channel: Multichannel Signal Imaging for PPG-to-ECG Reconstruction with Vision Transformers
Xiaoyan Li, Shixin Xu, Faisal Habib +2
Reconstructing ECG from PPG is a promising yet challenging task. While recent advancements in generative models have significantly improved ECG reconstruction, accurately capturing…