4 papers
Mapping Whole Exome Sequencing to In Vivo Imaging with Stereotactic Localization and Deep Learning
Mahsa Servati, Courtney N. Vaccaro, Emily E. Diller +6
This study presents a multi-faceted approach combining stereotactic biopsy with standard clinical open-craniotomy for sample collection, voxel-wise analysis of MR images, regressio…
Variation in correlation between prognosis and histologic feature based on biopsy selection
Emily Diller, Jason Parker
Glioblastoma multiform carries a dismal prognosis with poor response to gold standard treatment. Innovative data analysis methods have been developed to characterize tumor genomic…
Predicted disease compositions of human gliomas estimated from multiparametric MRI can predict endothelial proliferation, tumor grade, and overall survival
Emily E Diller, Sha Cao, Beth Ey +2
Background and Purpose: Biopsy is the main determinants of glioma clinical management, but require invasive sampling that fail to detect relevant features because of tumor heteroge…
Statistical multiscale mapping of IDH1, MGMT, and microvascular proliferation in human brain tumors from multiparametric MR and spatially-registered core biopsy
Jason G Parker, PhD, Emily E Diller +7
We propose a statistical multiscale mapping approach to identify microscopic and molecular heterogeneity across a tumor microenvironment using multiparametric MR (mp-MR). Twenty-ni…