activity
20182020
most citedThe signaling signature of the neurotensin type 1 receptor with endogenous ligands

72 citations · 114 across the 4 of their papers we have counts for

collaborators

4 papers

q-bio.BM2020★ 18 cited

Cell-penetrating pepducins targeting the neurotensin receptor type 1 relieve pain

Rebecca L. Brouillette, Élie Besserer-Offroy, Christine E. Mona +8

Pepducins are cell-penetrating, membrane-tethered lipopeptides designed to target the intracellular region of a G protein-coupled receptor (GPCR) in order to allosterically modulat…

q-bio.CB2019★ 19 cited

Computational model combined with in vitro experiments to analyse mechanotransduction during mesenchymal stem cell adhesion

Jean-Louis Milan, Sandrine Lavenus, Paul Pilet +5

The shape that stem cells reach at the end of adhesion process influences their differentiation. Rearrangement of cytoskeleton and modification of intracellular tension may activat…

q-bio.CB2019★ 5 cited

Label-free cell signaling pathway deconvolution of Angiotensin type 1 receptor reveals time-resolved G-protein activity and distinct AngII and AngIII\IV responses

Sandrine Lavenus, Élie Simard, Élie Besserer-Offroy +3

Angiotensin II (AngII) type 1 receptor (AT1R) is a G protein-coupled receptor known for its role in numerous physiological processes and its implication in many vascular diseases.…

q-bio.CB2018★ 72 cited

The signaling signature of the neurotensin type 1 receptor with endogenous ligands

Élie Besserer-Offroy, Rebecca L Brouillette, Sandrine Lavenus +8

The human neurotensin 1 receptor (hNTS1) is a G protein-coupled receptor involved in many physiological functions, including analgesia, hypothermia, and hypotension. To gain a bett…