3 papers
stat.AP2020
A Simultaneous Inference Procedure to Identify Subgroups from RCTs with Survival Outcomes: Application to Analysis of AMD Progression Studies
Yue Wei, Jason C. Hsu, Wei Chen +2
With the uptake of targeted therapies, instead of the "one-fits-all" approach, modern randomized clinical trials (RCTs) often aim to develop treatments that target a subgroup of pa…
stat.AP2019
Gene-based Association Analysis for Bivariate Time-to-event Data through Functional Regression with Copula Models
Yue Wei, Yi Liu, Wei Chen +1
Several gene-based association tests for time-to-event traits have been proposed recently, to detect whether a gene region (containing multiple variants), as a set, is associated w…
stat.ME2019
Copula-based Semiparametric Regression Method for Bivariate Data under General Interval Censoring
Tao Sun, Ying Ding
This research is motivated by discovering and underpinning genetic causes for the progression of a bilateral eye disease, Age-related Macular Degeneration (AMD), of which the prima…