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equivariant neural networks 1geometric deep learning 1multiscale hierarchical graphs 1protein representation learning 1structure-based prediction 1

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cs.LG2026

PRIME: Protein Representation via Physics-Informed Multiscale Equivariant Hierarchies

Viet Thanh Duy Nguyen, John K. Johnstone, Truong-Son Hy

The paper presents PRIME, a physics‑informed multiscale hierarchical graph framework that models proteins at five structural levels and enables bidirectional information flow, achi…