3 papers
q-bio.MN2020
Signaling activations through G-protein-coupled-receptor aggregations
Masaki Watabe, Hideaki Yoshimura, Satya N. V. Arjunan +2
Eukaryotic cells transmit extracellular signal information to cellular interiors through the formation of a ternary complex made up of a ligand (or agonist), G-protein, and G-prote…
q-bio.MN2019
Cooperativity transitions driven by higher-order oligomer formations in ligand-induced receptor dimerization
Masaki Watabe, Satya N. V. Arjunan, Wei Xiang Chew +2
While cooperativity in ligand-induced receptor dimerization has been linked with receptor-receptor couplings via minimal representations of physical observables, effects arising fr…
q-bio.SC2018
Surface reaction-diffusion kinetics on lattice at the microscopic scale
Wei-Xiang Chew, Kazunari Kaizu, Masaki Watabe +3
Microscopic models of reaction-diffusion processes on the cell membrane can link local spatiotemporal effects to macroscopic self-organized patterns often observed on the membrane.…