3 papers
q-bio.MN2020
Gain and Loss of Function mutations in biological chemical reaction networks: a mathematical model with application to colorectal cancer cells
Sara Sommariva, Giacomo Caviglia, Michele Piana
This paper studies a system of Ordinary Differential Equations modeling a chemical reaction network and derives from it a simulation tool mimicking Loss of Function and Gain of Fun…
q-bio.TO2020
Mathematical modelling of nuclear medicine data
Michele Piana, Giacomo Caviglia, Sara Sommariva
Positron Emission Tomography using 2-[18F]-2deoxy-D-glucose as radiotracer (FDG-PET) is currently one of the most frequently applied functional imaging methods in clinical applicat…
q-bio.TO2018
FDG kinetics in cells and tissues: a biochemically-driven compartmental approach
Mara Scussolini, Vanessa Cossu, Cecilia Marini +2
The radioactive glucose analogue 2-deoxy-2-[18F]fluoro-D-glucose (FDG) is widely used to reconstruct glucose metabolism and other biological functions in cells and tissues. The ana…