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causal trees 1heterogeneous treatment effect 1honest estimation 1significance-based splitting 1uplift modeling 1

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1 paper

stat.ME2026

Significance-First Splitting: Aligning Treatment Heterogeneity Detection with Honest Estimation

Pantelis Z. Hadjipantelis, Weng Man Chiang, Karthik Nagesh

The paper introduces a hybrid tree algorithm that merges significance‑based splitting with honest sample‑splitting to detect heterogeneous treatment effects while delivering valid…