activity
20182022
most citedDeepAffinity: Interpretable Deep Learning of Compound-Protein Affinity through Unified Recurrent and Convolutional Neural Networks

561 citations · 568 across the 6 of their papers we have counts for

collaborators

6 papers

cs.SD2022★ 2 cited

Deploying self-supervised learning in the wild for hybrid automatic speech recognition

Mostafa Karimi, Changliang Liu, Kenichi Kumatani +3

Self-supervised learning (SSL) methods have proven to be very successful in automatic speech recognition (ASR). These great improvements have been reported mostly based on highly c…

q-bio.MN2020

Network-principled deep generative models for designing drug combinations as graph sets

Mostafa Karimi, Arman Hasanzadeh, Yang shen

Combination therapy has shown to improve therapeutic efficacy while reducing side effects. Importantly, it has become an indispensable strategy to overcome resistance in antibiotic…

stat.ME2020

Directionally Dependent Multi-View Clustering Using Copula Model

Kahkashan Afrin, Ashif S. Iquebal, Mostafa Karimi +3

In recent biomedical scientific problems, it is a fundamental issue to integratively cluster a set of objects from multiple sources of datasets. Such problems are mostly encountere…

q-bio.BM2019★ 5 cited

Explainable Deep Relational Networks for Predicting Compound-Protein Affinities and Contacts

Mostafa Karimi, Di Wu, Zhangyang Wang +1

Predicting compound-protein affinity is critical for accelerating drug discovery. Recent progress made by machine learning focuses on accuracy but leaves much to be desired for int…

cs.CV2019

Illegible Text to Readable Text: An Image-to-Image Transformation using Conditional Sliced Wasserstein Adversarial Networks

Mostafa Karimi, Gopalkrishna Veni, Yen-Yun Yu

Automatic text recognition from ancient handwritten record images is an important problem in the genealogy domain. However, critical challenges such as varying noise conditions, va…

q-bio.BM2018★ 561 cited

DeepAffinity: Interpretable Deep Learning of Compound-Protein Affinity through Unified Recurrent and Convolutional Neural Networks

Mostafa Karimi, Di Wu, Zhangyang Wang +1

Motivation: Drug discovery demands rapid quantification of compound-protein interaction (CPI). However, there is a lack of methods that can predict compound-protein affinity from s…