activity
20202024
most citedExploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing

173 citations · 296 across the 7 of their papers we have counts for

collaborators

7 papers

q-bio.QM2024★ 3 cited

Privacy-Preserving Multi-Center Differential Protein Abundance Analysis with FedProt

Yuliya Burankova, Miriam Abele, Mohammad Bakhtiari +28

Quantitative mass spectrometry has revolutionized proteomics by enabling simultaneous quantification of thousands of proteins. Pooling patient-derived data from multiple institutio…

q-bio.QM2023★ 4 cited

Drugst.One -- A plug-and-play solution for online systems medicine and network-based drug repurposing

Andreas Maier, Michael Hartung, Mark Abovsky +36

In recent decades, the development of new drugs has become increasingly expensive and inefficient, and the molecular mechanisms of most pharmaceuticals remain poorly understood. In…

cs.LG2021★ 1 cited

The FeatureCloud AI Store for Federated Learning in Biomedicine and Beyond

Julian Matschinske, Julian Späth, Reza Nasirigerdeh +29

Machine Learning (ML) and Artificial Intelligence (AI) have shown promising results in many areas and are driven by the increasing amount of available data. However, this data is o…

cs.LG2021★ 3 cited

HyFed: A Hybrid Federated Framework for Privacy-preserving Machine Learning

Reza Nasirigerdeh, Reihaneh Torkzadehmahani, Julian Matschinske +3

Federated learning (FL) enables multiple clients to jointly train a global model under the coordination of a central server. Although FL is a privacy-aware paradigm, where raw data…

q-bio.QM2020★ 2 cited

Flimma: a federated and privacy-preserving tool for differential gene expression analysis

Olga Zolotareva, Reza Nasirigerdeh, Julian Matschinske +9

Aggregating transcriptomics data across hospitals can increase sensitivity and robustness of differential expression analyses, yielding deeper clinical insights. As data exchange i…

cs.CR2020★ 110 cited

Privacy-preserving Artificial Intelligence Techniques in Biomedicine

Reihaneh Torkzadehmahani, Reza Nasirigerdeh, David B. Blumenthal +22

Artificial intelligence (AI) has been successfully applied in numerous scientific domains. In biomedicine, AI has already shown tremendous potential, e.g. in the interpretation of…

q-bio.MN2020★ 173 cited

Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing

Sepideh Sadegh, Julian Matschinske, David B. Blumenthal +14

Coronavirus Disease-2019 (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus. It was first identified in Wuhan, China, and has since spread causing a global pandemic…