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stat.ME2025
Estimating heritability of survival traits using censored multiple variance component model
Do Hyun Kim, Hua Zhou, Brendon Chau +5
Characterizing the genetic basis of survival traits, such as age at disease onset, is critical for risk stratification, early intervention, and elucidating biological mechanisms th…
stat.ME2020
Survival Analysis Using a 5-Step Stratified Testing and Amalgamation Routine in Randomized Clinical Trials
Devan V. Mehrotra, Rachel Marceau West
Randomized clinical trials are often designed to assess whether a test treatment prolongs survival relative to a control treatment. Increased patient heterogeneity, while desirable…
stat.ME2019
PRISM: Patient Response Identifiers for Stratified Medicine
Thomas O. Jemielita, Devan V. Mehrotra
Pharmaceutical companies continue to seek innovative ways to explore whether a drug under development is likely to be suitable for all or only an identifiable stratum of patients i…