64 citations · 95 across the 8 of their papers we have counts for
8 papers
Stochastic Kinetic Study of Protein Aggregation and Molecular Crowding Effects of Ab40 and Ab42
John Bridstrup, Jian-Min Yuan, John S. Schreck
Two isoforms of beta amyloid peptides, Ab40 and Ab42, differ from each other only in the last two amino acids, IA, at the end of Ab42. They, however, differ significantly in their…
Stochastic kinetic treatment of protein aggregation and the effects of macromolecular crowding
John Bridstrup, John S Schreck, Jesse L Jorgenson +1
Investigation of protein self-assembly processes is important for the understanding of the growth processes of functional proteins as well as disease-causing amyloids. Inside cells…
A Kinetic Study of Amyloid Formation: Fibril Growth and Length Distributions
John S. Schreck, Jian-Min Yuan
We propose a kinetic model for the self-aggregation by amyloid proteins. By extending several well-known models for protein aggregation, the time evolution of aggregate concentrati…
Statistical Mechanical Treatments of Protein Amyloid Formation
John S. Schreck, Jian-Min Yuan
Protein aggregation is an important field of investigation because it is closely related to the problem of neurodegenerative diseases, to the development of biomaterials, and to th…
A Statistical Mechanical Approach to Protein Aggregation
John S. Schreck, Jian-Min Yuan
We develop a theory of aggregation using statistical mechanical methods. An example of a complicated aggregation system with several levels of structures is peptide/protein self-as…
Exactly Solvable Model for Helix-Coil-Sheet Transitions in Protein Systems
John S. Schreck, Jian-Min Yuan
In view of the important role helix-sheet transitions play in protein aggregation, we introduce a simple model to study secondary structural transitions of helix-coil-sheet systems…