1.9k citations · 2.8k across the 19 of their papers we have counts for
19 papers
Birth-death-suppression Markov process and wildfires
George Hulsey, David L. Alderson, Jean Carlson
Birth and death Markov processes can model stochastic physical systems from percolation to disease spread and, in particular, wildfires. We introduce and analyze a birth-death-supp…
Aging-induced fragility of the immune system
Eric W. Jones, Jiming Sheng, Jean M. Carlson +1
The adaptive and innate branches of the vertebrate immune system work in close collaboration to protect organisms from harmful pathogens. As an organism ages its immune system unde…
Navigation and control of outcomes in a generalized Lotka-Volterra model of the microbiome
Eric W. Jones, Parker Shankin-Clarke, Jean M. Carlson
The generalized Lotka-Volterra (gLV) equations model the microbiome as a collection of interacting ecological species. Here we use a particular experimentally-derived gLV model of…
Control of ecological outcomes through deliberate parameter changes in a model of the gut microbiome
Zipeng Wang, Eric W. Jones, Joshua M. Mueller +1
The generalized Lotka-Volterra (gLV) equations are a mathematical proxy for ecological dynamics. We focus on a gLV model of the gut microbiome, in which the evolution of the gut mi…
Characterization of fracture in topology-optimized bio-inspired networks
Chantal Nguyen, Darin Peetz, Ahmed E. Elbanna +1
Designing strong and robust bio-inspired structures requires an understanding of how function arises from the architecture and geometry of materials found in nature. We draw from t…
Network models for characterization of trabecular bone
Avik Mondal, Chantal Nguyen, Xiao Ma +2
Trabecular bone is a lightweight, compliant material organized as a web of struts and rods (trabeculae) that erode with age and the onset of bone diseases like osteoporosis, leadin…
Steady State Reduction of generalized Lotka-Volterra systems in the microbiome
Eric W. Jones, Jean M. Carlson
The generalized Lotka-Volterra (gLV) equations, a classic model from theoretical ecology, describe the population dynamics of a set of interacting species. As the number of species…
Collective Decision Dynamics in Group Evacuation: Modeling Tradeoffs and Optimal Behavior
Kimberly J. Schlesinger, Chantal Nguyen, Imtiaz Ali +1
Quantifying uncertainties in collective human behavior and decision making is crucial for ensuring public health and safety, enabling effective disaster response, informing the des…
Individual Differences in Dynamic Functional Brain Connectivity Across the Human Lifespan
Elizabeth N. Davison, Benjamin O. Turner, Kimberly J. Schlesinger +4
Individual differences in brain functional networks may be related to complex personal identifiers, including health, age, and ability. Understanding and quantifying these differen…
Collective Decision Dynamics in Group Evacuation: Behavioral Experiment and Machine Learning Models
Chantal Nguyen, Fangqiu Han, Kimberly J. Schlesinger +2
Identifying factors that affect human decision making and quantifying their influence remain essential and challenging tasks for the design and implementation of social and technol…
Optimizing Real-Time Vaccine Allocation in a Stochastic SIR Model
Chantal Nguyen, Jean M. Carlson
Real-time vaccination following an outbreak can effectively mitigate the damage caused by an infectious disease. However, in many cases, available resources are insufficient to vac…
Brain Network Adaptability Across Task States
Elizabeth N. Davison, Kimberly J. Schlesinger, Danielle S. Bassett +4
Activity in the human brain moves between diverse functional states to meet the demands of our dynamic environment, but fundamental principles guiding these transitions remain poor…
Optimal vaccination in a stochastic epidemic model of two non-interacting populations
Edwin C. Yuan, David L. Alderson, Sean Stromberg +1
Developing robust, quantitative methods to optimize resource allocations in response to epidemics has the potential to save lives and minimize health care costs. In this paper, we…
Coevolutionary immune system dynamics driving pathogen speciation
Kimberly J. Schlesinger, Sean P. Stromberg, Jean M. Carlson
We introduce and analyze a within-host dynamical model of the coevolution between rapidly mutating pathogens and the adaptive immune response. Pathogen mutation and a homeostatic c…
Resolving structural variability in network models and the brain
Florian Klimm, Danielle S. Bassett, Jean M. Carlson +1
Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architec…
Measuring and Modeling Behavioral Decision Dynamics in Collective Evacuation
Jean M. Carlson, David L. Alderson, Sean P. Stromberg +4
Identifying and quantifying factors influencing human decision making remains an outstanding challenge, impacting the performance and predictability of social and technological sys…
Collective Decision Dynamics in the Presence of External Drivers
Danielle S. Bassett, David L. Alderson, Jean M. Carlson
We develop a sequence of models describing information transmission and decision dynamics for a network of individual agents subject to multiple sources of influence. Our general f…
Robust Detection of Dynamic Community Structure in Networks
Danielle S. Bassett, Mason A. Porter, Nicholas F. Wymbs +3
We describe techniques for the robust detection of community structure in some classes of time-dependent networks. Specifically, we consider the use of statistical null models for…
Dynamic reconfiguration of human brain networks during learning
Danielle S. Bassett, Nicholas F. Wymbs, Mason A. Porter +3
Human learning is a complex phenomenon requiring flexibility to adapt existing brain function and precision in selecting new neurophysiological activities to drive desired behavior…