64 citations · 74 across the 7 of their papers we have counts for
7 papers
From the digital twins in healthcare to the Virtual Human Twin: a moon-shot project for digital health research
Marco Viceconti, Maarten De Vos, Sabato Mellone +1
The idea of a systematic digital representation of the entire known human pathophysiology, which we could call the Virtual Human Twin, has been around for decades. To date, most re…
Possible Contexts of Use for In Silico trials methodologies: a consensus-based review
Marco Viceconti, Luca Emili, Payman Afshari +15
The term "In Silico Trial" indicates the use of computer modelling and simulation to evaluate the safety and efficacy of a medical product, whether a drug, a medical device, a diag…
Verification of an agent-based disease model of human mycobacterium tuberculosis infection
Cristina Curreli, Francesco Pappalardo, Giulia Russo +5
Agent-Based Models are a powerful class of computational models widely used to simulate complex phenomena in many different application areas. However, one of the most critical asp…
In Silico Trial to test COVID-19 candidate vaccines: a case study with UISS platform
Giulia Russo, Marzio Pennisi, Marco Viceconti +1
SARS-CoV-2 is a severe respiratory infection that infects humans. Its outburst entitled it as a pandemic emergence. To get a grip on this, outbreak specific preventive and therapeu…
Generation of digital patients for the simulation of tuberculosis with UISS-TB
Marzio Pennisi, Miguel A. Juarez, Giulia Russo +2
EC funded STriTuVaD project aims to test, through a phase IIb clinical trial, two of the most advanced therapeutic vaccines against tuberculosis. In parallel, we have extended the…
Evaluation of the efficacy of RUTI and ID93/GLA-SE vaccines in tuberculosis treatment: in silico trial through UISS-TB simulator
Giulia Russo, Francesco Pappalardo, Miguel A. Juarez +5
Tuberculosis (TB) is one of the deadliest diseases worldwide, with 1,5 million fatalities every year along with potential devastating effects on society, families and individuals.…