13 citations · 13 across the 2 of their papers we have counts for
5 papers
Reconciling Kinetic and Equilibrium Models of Bacterial Transcription
Muir J. Morrison, Manuel Razo-Mejia, Rob Phillips
The study of transcription remains one of the centerpieces of modern biology with implications in settings from development to metabolism to evolution to disease. Precision measure…
First-principles prediction of the information processing capacity of a simple genetic circuit
Manuel Razo-Mejia, Sarah Marzen, Griffin Chure +3
Given the stochastic nature of gene expression, genetically identical cells exposed to the same environmental inputs will produce different outputs. This heterogeneity has been hyp…
The Energetics of Molecular Adaptation in Transcriptional Regulation
Griffin Chure, Manuel Razo-Mejia, Nathan M. Belliveau +5
Mutation is a critical mechanism by which evolution explores the functional landscape of proteins. Despite our ability to experimentally inflict mutations at will, it remains diffi…
Figure 1 Theory Meets Figure 2 Experiments in the Study of Gene Expression
Rob Phillips, Nathan M. Belliveau, Griffin Chure +3
It is tempting to believe that we now own the genome. The ability to read and re-write it at will has ushered in a stunning period in the history of science. Nonetheless, there is…
Tuning transcriptional regulation through signaling: A predictive theory of allosteric induction
Manuel Razo-Mejia, Stephanie L. Barnes, Nathan M. Belliveau +4
Allosteric regulation is found across all domains of life, yet we still lack simple, predictive theories that directly link the experimentally tunable parameters of a system to its…