16 citations · 20 across the 5 of their papers we have counts for
5 papers
Theoretical and computational tools to model multistable gene regulatory networks
Federico Bocci, Dongya Jia, Qing Nie +2
The last decade has witnessed a surge of theoretical and computational models to describe the dynamics of complex gene regulatory networks, and how these interactions can give rise…
Stochastic fluctuations promote ordered pattern formation of cells in the Notch-Delta signaling pathway
Madeline Galbraith, Federico Bocci, José N. Onuchic
The Notch-Delta signaling pathway mediates cell differentiation implicated in many regulatory processes including spatiotemporal patterning in tissues by promoting alternate cell f…
Understanding the principles of pattern formation driven by Notch signaling by integrating experiments and theoretical models
Federico Bocci, Jose Nelson Onuchic, Mohit Kumar Jolly
Notch signaling is an evolutionary conserved cell-cell communication pathway. Besides regulating cell-fate decisions at an individual cell level, Notch signaling coordinates the em…
Quantifying cancer epithelial-mesenchymal plasticity and its association with stemness and immune response
Dongya Jia, Xuefei Li, Federico Bocci +5
Cancer cells can acquire a spectrum of stable hybrid epithelial/mesenchymal (E/M) states during epithelial-mesenchymal transition (EMT). Cells in these hybrid E/M phenotypes often…
Deciphering the dynamics of Epithelial-Mesenchymal Transition and Cancer Stem Cells in tumor progression
Federico Bocci, Herbert Levine, José Nelson Onuchic +1
Purpose of review: The epithelial-Mesenchymal Transition (EMT) and the generation of Cancer Stem Cells (CSC) are two fundamental aspects contributing to tumor growth, acquisition o…