activity
20162026
most citedValidation, comparison, and combination of algorithms for automatic detection of pulmonary nodules in computed tomography images: the LUNA16 challenge

1.4k citations · 3.4k across the 30 of their papers we have counts for

collaborators

30 papers

cs.CV2026

Benchmarking Foundation Models for Renal Lesion Stratification in CT

Hartmut Häntze, Sarah de Boer, Myrthe Buser +7

The rapid proliferation of open-source medical foundation models (FMs) raises a practical question: how well do their pre-trained representations transfer to clinically relevant bu…

cs.CL2025★ 22 cited

Leveraging Open-Source Large Language Models for Clinical Information Extraction in Resource-Constrained Settings

Luc Builtjes, Joeran Bosma, Mathias Prokop +2

Medical reports contain rich clinical information but are often unstructured and written in domain-specific language, posing challenges for information extraction. While proprietar…

cs.CV2025★ 1 cited

Robust Renal Mass Segmentation on CT: A Validation Study of an AI-Based Framework

Sarah de Boer, Hartmut Häntze, Kiran Vaidhya Venkadesh +9

Renal mass segmentation has important potential to enhance the clinical workflow, especially in settings requiring quantitative assessments. Kidney volume could serve as an importa…

eess.IV2024★ 1 cited

The ULS23 Challenge: a Baseline Model and Benchmark Dataset for 3D Universal Lesion Segmentation in Computed Tomography

M. J. J. de Grauw, E. Th. Scholten, E. J. Smit +4

Size measurements of tumor manifestations on follow-up CT examinations are crucial for evaluating treatment outcomes in cancer patients. Efficient lesion segmentation can speed up…

eess.IV2024★ 16 cited

MRSegmentator: Multi-Modality Segmentation of 40 Classes in MRI and CT

Hartmut Häntze, Lina Xu, Christian J. Mertens +29

Purpose: To develop and evaluate a deep learning model for multi-organ segmentation of MRI scans. Materials and Methods: The model was trained on 1,200 manually annotated 3D axial…

eess.IV2023★ 2 cited

Transfer learning from a sparsely annotated dataset of 3D medical images

Gabriel Efrain Humpire-Mamani, Colin Jacobs, Mathias Prokop +2

Transfer learning leverages pre-trained model features from a large dataset to save time and resources when training new models for various tasks, potentially enhancing performance…

eess.IV2023

Kidney abnormality segmentation in thorax-abdomen CT scans

Gabriel Efrain Humpire Mamani, Nikolas Lessmann, Ernst Th. Scholten +3

In this study, we introduce a deep learning approach for segmenting kidney parenchyma and kidney abnormalities to support clinicians in identifying and quantifying renal abnormalit…

eess.IV2023★ 7 cited

Emphysema Subtyping on Thoracic Computed Tomography Scans using Deep Neural Networks

Weiyi Xie, Colin Jacobs, Jean-Paul Charbonnier +2

Accurate identification of emphysema subtypes and severity is crucial for effective management of COPD and the study of disease heterogeneity. Manual analysis of emphysema subtypes…

eess.IV2023★ 93 cited

Lumbar spine segmentation in MR images: a dataset and a public benchmark

Jasper W. van der Graaf, Miranda L. van Hooff, Constantinus F. M. Buckens +6

This paper presents a large publicly available multi-center lumbar spine magnetic resonance imaging (MRI) dataset with reference segmentations of vertebrae, intervertebral discs (I…

eess.IV2023★ 1 cited

Uncertainty-Aware Multiple-Instance Learning for Reliable Classification: Application to Optical Coherence Tomography

Coen de Vente, Bram van Ginneken, Carel B. Hoyng +2

Deep learning classification models for medical image analysis often perform well on data from scanners that were used during training. However, when these models are applied to da…

cs.CV2023★ 204 cited

Understanding metric-related pitfalls in image analysis validation

Annika Reinke, Minu D. Tizabi, Michael Baumgartner +75

Validation metrics are key for the reliable tracking of scientific progress and for bridging the current chasm between artificial intelligence (AI) research and its translation int…

eess.IV2022★ 1 cited

Domain adaptation strategies for cancer-independent detection of lymph node metastases

Péter Bándi, Maschenka Balkenhol, Marcory van Dijk +3

Recently, large, high-quality public datasets have led to the development of convolutional neural networks that can detect lymph node metastases of breast cancer at the level of ex…

cs.CV2022★ 469 cited

Metrics reloaded: Recommendations for image analysis validation

Lena Maier-Hein, Annika Reinke, Patrick Godau +71

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen…

eess.IV2021★ 1 cited

Learn2Reg: comprehensive multi-task medical image registration challenge, dataset and evaluation in the era of deep learning

Alessa Hering, Lasse Hansen, Tony C. W. Mok +50

Image registration is a fundamental medical image analysis task, and a wide variety of approaches have been proposed. However, only a few studies have comprehensively compared medi…

cs.CV2021

Robust Segmentation Models using an Uncertainty Slice Sampling Based Annotation Workflow

Grzegorz Chlebus, Andrea Schenk, Horst K. Hahn +2

Semantic segmentation neural networks require pixel-level annotations in large quantities to achieve a good performance. In the medical domain, such annotations are expensive, beca…

eess.IV2021

Deep Clustering Activation Maps for Emphysema Subtyping

Weiyi Xie, Colin Jacobs, Bram van Ginneken

We propose a deep learning clustering method that exploits dense features from a segmentation network for emphysema subtyping from computed tomography (CT) scans. Using dense featu…

eess.IV2021★ 16 cited

Automated Estimation of Total Lung Volume using Chest Radiographs and Deep Learning

Ecem Sogancioglu, Keelin Murphy, Ernst Th. Scholten +3

Total lung volume is an important quantitative biomarker and is used for the assessment of restrictive lung diseases. In this study, we investigate the performance of several deep-…

eess.IV2021★ 1 cited

Dense Regression Activation Maps For Lesion Segmentation in CT scans of COVID-19 patients

Weiyi Xie, Colin Jacobs, Jean-Paul Charbonnier +1

Automatic lesion segmentation on thoracic CT enables rapid quantitative analysis of lung involvement in COVID-19 infections. However, obtaining a large amount of voxel-level annota…

cs.CR2020★ 129 cited

Adversarial Attack Vulnerability of Medical Image Analysis Systems: Unexplored Factors

Gerda Bortsova, Cristina González-Gonzalo, Suzanne C. Wetstein +9

Adversarial attacks are considered a potentially serious security threat for machine learning systems. Medical image analysis (MedIA) systems have recently been argued to be vulner…

eess.IV2020★ 102 cited

Relational Modeling for Robust and Efficient Pulmonary Lobe Segmentation in CT Scans

Weiyi Xie, Colin Jacobs, Jean-Paul Charbonnier +1

Pulmonary lobe segmentation in computed tomography scans is essential for regional assessment of pulmonary diseases. Recent works based on convolution neural networks have achieved…

cs.CV2019★ 36 cited

Iterative Augmentation of Visual Evidence for Weakly-Supervised Lesion Localization in Deep Interpretability Frameworks: Application to Color Fundus Images

Cristina González-Gonzalo, Bart Liefers, Bram van Ginneken +1

Interpretability of deep learning (DL) systems is gaining attention in medical imaging to increase experts' trust in the obtained predictions and facilitate their integration in cl…

eess.IV2019

Vertebra partitioning with thin-plate spline surfaces steered by a convolutional neural network

Nikolas Lessmann, Jelmer M. Wolterink, Majd Zreik +3

Thin-plate splines can be used for interpolation of image values, but can also be used to represent a smooth surface, such as the boundary between two structures. We present a meth…

cs.CV2019★ 110 cited

Evaluation of a deep learning system for the joint automated detection of diabetic retinopathy and age-related macular degeneration

Cristina González-Gonzalo, Verónica Sánchez-Gutiérrez, Paula Hernández-Martínez +5

Purpose: To validate the performance of a commercially-available, CE-certified deep learning (DL) system, RetCAD v.1.3.0 (Thirona, Nijmegen, The Netherlands), for the joint automat…

eess.IV2019★ 124 cited

Computer aided detection of tuberculosis on chest radiographs: An evaluation of the CAD4TB v6 system

Keelin Murphy, Shifa Salman Habib, Syed Mohammad Asad Zaidi +10

There is a growing interest in the automated analysis of chest X-Ray (CXR) as a sensitive and inexpensive means of screening susceptible populations for pulmonary tuberculosis. In…