8 citations · 17 across the 3 of their papers we have counts for
5 papers
Data augmentation and multimodal learning for predicting drug response in patient-derived xenografts from gene expressions and histology images
Alexander Partin, Thomas Brettin, Yitan Zhu +7
Patient-derived xenografts (PDXs) are an appealing platform for preclinical drug studies because the in vivo environment of PDXs helps preserve tumor heterogeneity and usually bett…
A cross-study analysis of drug response prediction in cancer cell lines
Fangfang Xia, Jonathan Allen, Prasanna Balaprakash +21
To enable personalized cancer treatment, machine learning models have been developed to predict drug response as a function of tumor and drug features. However, most algorithm deve…
Learning Curves for Drug Response Prediction in Cancer Cell Lines
Alexander Partin, Thomas Brettin, Yvonne A. Evrard +9
Motivated by the size of cell line drug sensitivity data, researchers have been developing machine learning (ML) models for predicting drug response to advance cancer treatment. As…
Ensemble Transfer Learning for the Prediction of Anti-Cancer Drug Response
Yitan Zhu, Thomas Brettin, Yvonne A. Evrard +6
Transfer learning has been shown to be effective in many applications in which training data for the target problem are limited but data for a related (source) problem are abundant…
A Systematic Approach to Featurization for Cancer Drug Sensitivity Predictions with Deep Learning
Austin Clyde, Tom Brettin, Alexander Partin +6
By combining various cancer cell line (CCL) drug screening panels, the size of the data has grown significantly to begin understanding how advances in deep learning can advance dru…