3 papers
cond-mat.soft2024
A Functional Human Liver Tissue Model: 3D Bioprinted Co-culture Discoids
Vignesh Subramaniam, Carolina Abrahan, Brett R. Higgins +6
To reduce costs and delays related to developing new and effective drugs, there is a critical need for improved human liver tissue models. Here we describe an approach for 3D biopr…
cond-mat.soft2024
Elastic Modulus Versus Cell Packing Density in MDCK Epithelial Monolayers
Steven J. Chisolm, Emily Guo, Vignesh Subramaniam +2
The elastic moduli of tissues are connected to their states of health and function. The epithelial monolayer is a simple, minimal, tissue model that is often used to gain understan…
cond-mat.soft2024
Transitions Between Cooperative and Crowding-Dominated Collective Motion in non-Jammed MDCK Monolayers
Steven J. Chisolm, Emily Guo, Vignesh Subramaniam +2
Transitions between solid-like and fluid-like states in living tissues have been found in steps of embryonic development and in stages of disease progression. Our current understan…