46 citations · 213 across the 8 of their papers we have counts for
8 papers
Facile One Pot Synthesis of Hybrid Core-Shell Silica-Based Sensors for Live Imaging of Dissolved Oxygen and Hypoxia Mapping in 3D cell models
Helena Iuele, Stefania Forciniti, Valentina Onesto +6
Fluorescence imaging allows for non-invasively visualizing and measuring key physiological parameters like pH and dissolved oxygen. In our work, we created two ratiometric fluoresc…
A pH Sensor Scaffold for Mapping Spatiotemporal Gradients in Three Dimensional In Vitro Tumour Models
Riccardo Rizzo, Valentina Onesto, Stefania Forciniti +6
The detection of extracellular pH at single cell resolution is challenging and requires advanced sensibility. Sensing pH at a high spatial and temporal resolution might provide cru…
Fluorescent nano- and microparticles for sensing cellular microenvironment: past, present and future applications
Giuliana Grasso, Francesco Colella, Stefania Forciniti +7
The tumor microenvironment (TME) features distinct hallmarks, including acidosis, hypoxia, reactive oxygen species (ROS) generation, and altered ion fluxes, which are crucial targe…
Highly sensitive fluorescent pH microsensor based on the ratiometric dye pyranine immobilized on silica microparticles
Anil Chandra, Saumya Prasad, Helena Iuele +5
Pyranine (HPTS) is a remarkably interesting pH sensitive dye that has been used for plenty of applications. Its high quantum yield and extremely sensitive ratiometric fluorescence…
Probing the pH microenvironment of mesenchymal stromal cell cultures on additive-manufactured scaffolds
Ivan Lorenzo Moldero, Anil Chandra, Marta Cavo +5
Despite numerous advances in the field of tissue engineering and regenerative medicine, monitoring the formation of tissue regeneration and its metabolic variations during culture…
Optical and magnetic resonance imaging approaches for investigating the tumour microenvironment: state-of-the-art review and future trends
S. Prasad, A. Chandra, M. Cavo +8
The tumour microenvironment (TME) strongly influences tumorigenesis and metastasis. Two of the most characterized properties of the TME are acidosis and hypoxia, both of which are…