bayesian clinical trials 1external data integration 1hybrid-controlled designs 1pediatric trials 1sample size determination 1
From the 1 of 3 linked papers with an AI index.
3 papers
stat.ME2026
Modification and extension of the Bayesian clinical trial design using external data for single-arm and hybrid-controlled trials
Wataru Murasaki, Tomohiro Ohigashi, Ryota Ishii +2
The paper proposes revised Bayesian prior specifications and extends a simulation‑based framework to incorporate external data in single‑arm and hybrid‑controlled pediatric clinica…
stat.ME2026
Posterior Quantification of Borrowing from Multiple Historical Control Data in Bayesian Dynamic Borrowing Methods: A Scoping Review
Tomohiro Ohigashi, Wataru Murasaki, Masahiko Gosho
Bayesian dynamic borrowing methods incorporate historical control data into current clinical trial analyses while allowing the degree of borrowing to depend on the compatibility be…
stat.ME2024
Nonparametric Bayesian approach for dynamic borrowing of historical control data
Tomohiro Ohigashi, Kazushi Maruo, Takashi Sozu +1
When incorporating historical control data into the analysis of current randomized controlled trial data, it is critical to account for differences between the datasets. When the c…