From the 1 of 8 linked papers with an AI index.
8 papers
Modification and extension of the Bayesian clinical trial design using external data for single-arm and hybrid-controlled trials
Wataru Murasaki, Tomohiro Ohigashi, Ryota Ishii +2
The paper proposes revised Bayesian prior specifications and extends a simulation‑based framework to incorporate external data in single‑arm and hybrid‑controlled pediatric clinica…
Posterior Quantification of Borrowing from Multiple Historical Control Data in Bayesian Dynamic Borrowing Methods: A Scoping Review
Tomohiro Ohigashi, Wataru Murasaki, Masahiko Gosho
Bayesian dynamic borrowing methods incorporate historical control data into current clinical trial analyses while allowing the degree of borrowing to depend on the compatibility be…
Efficient Bayesian Inference in the Cox Model via Rank-Ordered Likelihood
Tomohiro Ohigashi, Shunichiro Orihara, Shonosuke Sugasawa
In Bayesian inference for the Cox proportional hazards model, modeling the baseline hazard function is challenging. Recently, direct Bayesian inference using the partial likelihood…
Efficient Prior Sensitivity and Tipping-point Analysis for Medical Research: Revisiting Sampling Importance Resampling
Tomohiro Ohigashi, Shonosuke Sugasawa
Bayesian methods have received increasing attention in medical research, where sensitivity analysis of prior distributions is essential. Such analyses typically require the evaluat…
Sample size re-estimation in blinded hybrid-control design using inverse probability weighting
Masahiro Kojima, Shunichiro Orihara, Keisuke Hanada +1
With the increasing availability of data from historical studies and real-world data sources, hybrid control designs that incorporate external data into the evaluation of current s…
Evaluating marginal likelihood approximations of dose-response relationship models in Bayesian benchmark dose methods for risk assessment
Sota Minewaki, Tomohiro Ohigashi, Takashi Sozu
Benchmark dose (BMD; a dose associated with a specified change in response) is used to determine the point of departure for the acceptable daily intake of substances for humans. Mu…