3 papers
stat.ME2021
Assessing contribution of treatment phases through tipping point analyses via counterfactual elicitation using rank preserving structural failure time models
Sudipta Bhattacharya, Jyotirmoy Dey
This article provides a novel approach to assess the importance of specific treatment phases within a treatment regimen through tipping point analyses (TPA) of a time-to-event endp…
stat.ME2020
Assessing contribution of treatment phases through tipping point analyses using rank preserving structural failure time models
Sudipta Bhattacharya, Jyotirmoy Dey
In clinical trials, an experimental treatment is sometimes added on to a standard of care or control therapy in multiple treatment phases (e.g., concomitant and maintenance phases)…
q-bio.OT2020
Statistical Issues and Recommendations for Clinical Trials Conducted During the COVID-19 Pandemic
R. Daniel Meyer, Bohdana Ratitch, Marcel Wolbers +15
The COVID-19 pandemic has had and continues to have major impacts on planned and ongoing clinical trials. Its effects on trial data create multiple potential statistical issues. Th…