4 papers
Growth and Collapse of an Isolated Bubble Driven by a Single Negative Histotripsy Cycle in Agarose Gel: Stress, Strain, and Strain Rate Fields
Lauren Mancia, Jonathan R. Sukovich, Zhen Xu +1
Histotripsy relies on cavitation to mechanically homogenize soft tissue. There is strong evidence that the high stresses, strains, and strain rates developed as bubbles grow and co…
Acoustic Cavitation Rheometry
Lauren Mancia, Jin Yang, Jean-Sebastien Spratt +5
Characterization of soft materials is challenging due to their high compliance and the strain-rate dependence of their mechanical properties. The inertial microcavitation-based hig…
Single-bubble dynamics in histotripsy and high-amplitude ultrasound: Modeling and validation
Lauren Mancia, Mauro Rodriguez, Jonathan Sukovich +2
A variety of approaches have been used to model the dynamics of a single, isolated bubble nucleated by a microsecond length high-amplitude ultrasound pulse (e.g., a histotripsy pul…
Acoustic measurements of the nucleus size distribution at the cavitation threshold
Lauren Mancia, Mauro Rodriguez, Jonathan Sukovich +3
Understanding the acoustic cavitation threshold is essential for minimizing cavitation bioeffects in diagnostic ultrasound and for controlling cavitation--mediated tissue ablation…