3 papers
stat.AP2023
Hybrid sample size calculations for cluster randomised trials using assurance
S. Faye Williamson, Svetlana V. Tishkovskaya, Kevin J. Wilson
Sample size determination for cluster randomised trials (CRTs) is challenging as it requires robust estimation of the intra-cluster correlation coefficient (ICC). Typically, the sa…
stat.ME2021
Bayesian sample size determination for diagnostic accuracy studies
Kevin J. Wilson, S. Faye Williamson, A. Joy Allen +3
The development of a new diagnostic test ideally follows a sequence of stages which, amongst other aims, evaluate technical performance. This includes an analytical validity study,…
q-bio.QM2020
Efficient adaptive designs for clinical trials of interventions for COVID-19
Nigel Stallard, Lisa Hampson, Norbert Benda +14
The COVID-19 pandemic has led to an unprecedented response in terms of clinical research activity. An important part of this research has been focused on randomized controlled clin…