11 citations · 20 across the 7 of their papers we have counts for
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stat.ME2019★ 3 cited
A Bayesian hierarchical model for bridging across patient subgroups in phase I clinical trials with animal data
Haiyan Zheng, Lisa V. Hampson, Thomas Jaki
Incorporating preclinical animal data, which can be regarded as a special kind of historical data, into phase I clinical trials can improve decision making when very little about h…
stat.AP2019★ 11 cited
A Bayesian decision-theoretic approach to incorporate preclinical information into phase I oncology trials
Haiyan Zheng, Lisa V. Hampson
Leveraging preclinical animal data for a phase I first-in-man trial is appealing yet challenging. A prior based on animal data may place large probability mass on values of the dos…