3 citations · 6 across the 4 of their papers we have counts for
3 papers · 1 filter
Joint modelling of longitudinal and time-to-event data applied to group sequential clinical trials
Abigail J. Burdon, Lisa V. Hampson, Christopher Jennison
Often in Phase 3 clinical trials measuring a long-term time-to-event endpoint, such as overall survival or progression-free survival, investigators also collect repeated measures o…
Eliciting judgements about dependent quantities of interest: The SHELF extension and copula methods illustrated using an asthma case study
Björn Holzhauer, Lisa V. Hampson, John Paul Gosling +8
Pharmaceutical companies regularly need to make decisions about drug development programs based on the limited knowledge from early stage clinical trials. In this situation, elicit…
A Bayesian hierarchical model for bridging across patient subgroups in phase I clinical trials with animal data
Haiyan Zheng, Lisa V. Hampson, Thomas Jaki
Incorporating preclinical animal data, which can be regarded as a special kind of historical data, into phase I clinical trials can improve decision making when very little about h…