DiffFit: Visually-Guided Differentiable Fitting of Molecule Structures to a Cryo-EM Map

Deng Luo, Zainab Alsuwaykit, Dawar Khan +3

We introduce DiffFit, a differentiable algorithm for fitting protein atomistic structures into an experimental reconstructed Cryo-Electron Microscopy (cryo-EM) volume map. In struc…