172 citations · 217 across the 7 of their papers we have counts for
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Bridging microscopic cell dynamics to nematohydrodynamics of cell monolayers
Aleksandra Ardaševa, Romain Mueller, Amin Doostmohammadi
It is increasingly being realized that liquid-crystalline features can play an important role in the properties and dynamics of cell monolayers. Here, we present a cell-based model…
Fluctuation-induced dynamics of nematic topological defects
Lasse Bonn, Aleksandra Ardaseva, Romain Mueller +2
Topological defects are increasingly being identified in various biological systems, where their characteristic flow fields and stress patterns are associated with continuous activ…
Half-integer and full-integer topological defects in polar active matter: Emergence, crossover, and coexistence
Aboutaleb Amiri, Romain Mueller, Amin Doostmohammadi
The presence and significance of active topological defects is increasingly realised in diverse biological and biomimetic systems. We introduce a continuum model of polar active ma…
Phase field models of active matter
Romain Mueller, Amin Doostmohammadi
We present an overview of phase field modeling of active matter systems as a tool for capturing various aspects of complex and active interfaces. We first describe how interfaces b…
Active Inter-cellular Forces in Collective Cell Motility
Guanming Zhang, Romain Mueller, Amin Doostmohammadi +1
The collective behaviour of confluent cell sheets is strongly influenced both by polar forces, arising through cytoskeletal propulsion and by active inter-cellular forces, which ar…
Active Matter Invasion
Felix Kempf, Romain Mueller, Erwin Frey +2
Biological active materials such as bacterial biofilms and eukaryotic cells thrive in confined micro-spaces. Here, we show through numerical simulations that confinement can serve…
Emergence of active nematic behaviour in monolayers of isotropic cells
Romain Mueller, Julia Yeomans, Amin Doostmohammadi
There is now growing evidence of the emergence and biological functionality of liquid crystal features, including nematic order and topological defects, in cellular tissues. Howeve…