7 citations · 8 across the 6 of their papers we have counts for
8 papers
Possible Contexts of Use for In Silico trials methodologies: a consensus-based review
Marco Viceconti, Luca Emili, Payman Afshari +15
The term "In Silico Trial" indicates the use of computer modelling and simulation to evaluate the safety and efficacy of a medical product, whether a drug, a medical device, a diag…
Verification of an agent-based disease model of human mycobacterium tuberculosis infection
Cristina Curreli, Francesco Pappalardo, Giulia Russo +5
Agent-Based Models are a powerful class of computational models widely used to simulate complex phenomena in many different application areas. However, one of the most critical asp…
Multiple Sclerosis disease: a computational approach for investigating its drug interactions
Simone Pernice, Marco Beccuti, Greta Romano +10
Multiple Sclerosis (MS) is a chronic and potentially highly disabling disease that can cause permanent damage and deterioration of the central nervous system. In Europe it is the l…
In Silico Trial to test COVID-19 candidate vaccines: a case study with UISS platform
Giulia Russo, Marzio Pennisi, Marco Viceconti +1
SARS-CoV-2 is a severe respiratory infection that infects humans. Its outburst entitled it as a pandemic emergence. To get a grip on this, outbreak specific preventive and therapeu…
Generation of digital patients for the simulation of tuberculosis with UISS-TB
Marzio Pennisi, Miguel A. Juarez, Giulia Russo +2
EC funded STriTuVaD project aims to test, through a phase IIb clinical trial, two of the most advanced therapeutic vaccines against tuberculosis. In parallel, we have extended the…
Evaluation of the efficacy of RUTI and ID93/GLA-SE vaccines in tuberculosis treatment: in silico trial through UISS-TB simulator
Giulia Russo, Francesco Pappalardo, Miguel A. Juarez +5
Tuberculosis (TB) is one of the deadliest diseases worldwide, with 1,5 million fatalities every year along with potential devastating effects on society, families and individuals.…