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q-bio.SC2020★ 8 cited
Modeling tau transport in the axon initial segment
Ivan A. Kuznetsov, Andrey V. Kuznetsov
By assuming that tau protein can be in seven kinetic states, we developed a model of tau protein transport in the axon and in the axon initial segment (AIS). Two separate sets of k…
q-bio.SC2019
How old are dense core vesicles residing in en passant boutons: Simulation of the mean age of dense core vesicles in axonal arbors accounting for resident and transiting vesicle populations
I. A. Kuznetsov, A. V. Kuznetsov
In neurons, neuropeptides are synthesized in the soma and are then transported along the axon in dense core vesicles (DCVs). DCVs are captured in varicosities located along the axo…