activity
20182026
most citedA Physics-Guided Modular Deep-Learning Based Automated Framework for Tumor Segmentation in PET Images

58 citations · 143 across the 40 of their papers we have counts for

collaborators

43 papers

eess.AS2026

HE-NAC: High-Efficiency Neural Audio Coding via Hierarchical and Residual Multi-Band Quantization

Darius Pétermann, Wootaek Lim, Seungkwon Beack +1

High-fidelity audio coding requires faithful reconstruction of perceptually important high-frequency components, which are often lost due to the aggressive temporal decimation and…

eess.IV2025

SPASHT: An image-enhancement method for sparse-view MPI SPECT

Zezhang Yang, Zitong Yu, Nuri Choi +4

Single-photon emission computed tomography for myocardial perfusion imaging (MPI SPECT) is a widely used diagnostic tool for coronary artery disease. However, the procedure require…

physics.med-ph2025

Progress in SPECT and PET Reconstruction for Theranostics: From Diagnosis to Therapy

Kweku Enninful, Fardeen Ahmed, Bradley Girod +4

The theranostic paradigm enables personalization of treatment by selecting patients with a diagnostic radiopharmaceutical and monitoring therapy using a matched therapeutic isotope…

physics.med-ph2025

Development and in silico imaging trial evaluation of a deep-learning-based transmission-less attenuation compensation method for DaT SPECT

Zitong Yu, Md Ashequr Rahman, Zekun Li +7

Quantitative measures of dopamine transporter (DaT) uptake in caudate, putamen, and globus pallidus derived from DaT-single-photon emission computed tomography (SPECT) images are b…

cs.CV2025

A detection-task-specific deep-learning method to improve the quality of sparse-view myocardial perfusion SPECT images

Zezhang Yang, Zitong Yu, Nuri Choi +1

Myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT) is a widely used and cost-effective diagnostic tool for coronary artery disease. However,…

physics.med-ph2025

ISIT-GEN: An in silico imaging trial to assess the inter-scanner generalizability of CTLESS for myocardial perfusion SPECT on defect-detection task

Zitong Yu, Nu Ri Choi, Zezhang Yang +3

A recently proposed scatter-window and deep learning-based attenuation compensation (AC) method for myocardial perfusion imaging (MPI) by single-photon emission computed tomography…

physics.med-ph2024

CTLESS: A scatter-window projection and deep learning-based transmission-less attenuation compensation method for myocardial perfusion SPECT

Zitong Yu, Md Ashequr Rahman, Craig K. Abbey +4

Attenuation compensation (AC), while being beneficial for visual-interpretation tasks in myocardial perfusion imaging (MPI) by SPECT, typically requires the availability of a separ…

physics.med-ph2024

Nuclear Medicine AI in Action: The Bethesda Report (AI Summit 2024)

Arman Rahmim, Tyler J. Bradshaw, Guido Davidzon +10

The 2nd SNMMI Artificial Intelligence (AI) Summit, organized by the SNMMI AI Task Force, took place in Bethesda, MD, on February 29 - March 1, 2024. Bringing together various commu…

physics.med-ph2024

Can patient-specific acquisition protocol improve performance on defect detection task in myocardial perfusion SPECT?

Nu Ri Choi, Md Ashequr Rahman, Zitong Yu +2

Myocardial perfusion imaging using single-photon emission computed tomography (SPECT), or myocardial perfusion SPECT (MPS) is a widely used clinical imaging modality for the diagno…

physics.med-ph2024

WIN-PDQ: A Wiener-estimator-based projection-domain quantitative SPECT method that accounts for intra-regional uptake heterogeneity

Zekun Li, Nadia Benabdallah, Daniel L. J. Thorek +1

SPECT can enable the quantification of activity uptake in lesions and at-risk organs in α-particle-emitting radiopharmaceutical therapies (α-RPTs). But this quantification is chall…

physics.med-ph2023★ 1 cited

Observer study-based evaluation of TGAN architecture used to generate oncological PET images

Roberto Fedrigo, Fereshteh Yousefirizi, Ziping Liu +9

The application of computer-vision algorithms in medical imaging has increased rapidly in recent years. However, algorithm training is challenging due to limited sample sizes, lack…

math.NA2023★ 2 cited

Domain Decomposition Method for Poisson--Boltzmann Equations based on Solvent Excluded Surface

Abhinav Jha, Benjamin Stamm

In this paper, we develop a domain decomposition method for the nonlinear Poisson-Boltzmann equation based on a solvent-excluded surface widely used in computational chemistry. The…

physics.med-ph2023

DEMIST: A deep-learning-based task-specific denoising approach for myocardial perfusion SPECT

Md Ashequr Rahman, Zitong Yu, Richard Laforest +3

There is an important need for methods to process myocardial perfusion imaging (MPI) SPECT images acquired at lower radiation dose and/or acquisition time such that the processed i…

physics.med-ph2023

A list-mode multi-energy window low-count SPECT reconstruction method for isotopes with multiple emission peaks

Md Ashequr Rahman, Zekun Li, Zitong Yu +3

SPECT provides a mechanism to perform absorbed-dose quantification tasks for -particle radiopharmaceutical therapies (-RPTs). However, quantitative SPECT for -RPT is chall…

eess.IV2023

A quality assurance framework for real-time monitoring of deep learning segmentation models in radiotherapy

Xiyao Jin, Yao Hao, Jessica Hilliard +5

To safely deploy deep learning models in the clinic, a quality assurance framework is needed for routine or continuous monitoring of input-domain shift and the models' performance…

physics.med-ph2023★ 2 cited

Joint regional uptake quantification of Thorium-227 and Radium-223 using a multiple-energy-window projection-domain quantitative SPECT method

Zekun Li, Nadia Benabdallah, Richard Laforest +3

Thorium-227-based alpha-particle radiopharmaceutical therapies (α-RPTs) are being investigated in several clinical and pre-clinical studies. After administration, Thorium-227 decay…

eess.IV2023

Need for Objective Task-based Evaluation of Deep Learning-Based Denoising Methods: A Study in the Context of Myocardial Perfusion SPECT

Zitong Yu, Md Ashequr Rahman, Richard Laforest +5

Artificial intelligence-based methods have generated substantial interest in nuclear medicine. An area of significant interest has been using deep-learning (DL)-based approaches fo…

physics.med-ph2023

Development and task-based evaluation of a scatter-window projection and deep learning-based transmission-less attenuation compensation method for myocardial perfusion SPECT

Zitong Yu, Md Ashequr Rahman, Craig K. Abbey +2

Attenuation compensation (AC) is beneficial for visual interpretation tasks in single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). However, tradi…

physics.med-ph2023★ 7 cited

Need for objective task-based evaluation of AI-based segmentation methods for quantitative PET

Ziping Liu, Joyce C. Mhlanga, Barry A. Siegel +1

Artificial intelligence (AI)-based methods are showing substantial promise in segmenting oncologic positron emission tomography (PET) images. For clinical translation of these meth…

eess.IV2023★ 1 cited

A task-specific deep-learning-based denoising approach for myocardial perfusion SPECT

Md Ashequr Rahman, Zitong Yu, Barry A. Siegel +1

Deep-learning (DL)-based methods have shown significant promise in denoising myocardial perfusion SPECT images acquired at low dose. For clinical application of these methods, eval…

physics.med-ph2022★ 2 cited

Issues and Challenges in Applications of Artificial Intelligence to Nuclear Medicine -- The Bethesda Report (AI Summit 2022)

Arman Rahmim, Tyler J. Bradshaw, Irène Buvat +10

The SNMMI Artificial Intelligence (SNMMI-AI) Summit, organized by the SNMMI AI Task Force, took place in Bethesda, MD on March 21-22, 2022. It brought together various community me…

physics.med-ph2022

Ideal-observer computation with anthropomorphic phantoms using Markov Chain Monte Carlo

Md Ashequr Rahman, Zitong Yu, Abhinav K. Jha

In medical imaging, it is widely recognized that image quality should be objectively evaluated based on performance in clinical tasks. To evaluate performance in signal-detection t…

physics.med-ph2022

No-gold-standard evaluation of quantitative imaging methods in the presence of correlated noise

Ziping Liu, Zekun Li, Joyce C. Mhlanga +2

Objective evaluation of quantitative imaging (QI) methods with patient data is highly desirable, but is hindered by the lack or unreliability of an available gold standard. To addr…

physics.med-ph2022

Investigating the limited performance of a deep-learning-based SPECT denoising approach: An observer-study-based characterization

Zitong Yu, Md Ashequr Rahman, Abhinav K. Jha

Multiple objective assessment of image-quality-based studies have reported that several deep-learning-based denoising methods show limited performance on signal-detection tasks. Ou…