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stat.ME2026
Simulation-Free Bayesian Power and Sample Size Calculations for Bayes Factors in Single-Arm Phase II Trials with Binary Endpoints
Riko Kelter, Kathrin Möllenhoff
Bayes factors provide a coherent Bayesian measure of evidence for competing hypotheses and have recently been used as the basis for single-arm phase II trial designs with binary en…
stat.ME2026
Optimal sequential two-stage Bayes Factor Design for two-arm clinical Phase II Trials with binary Endpoints
Riko Kelter
Two-arm phase II clinical trials often benefit from an interim analysis that allows early stopping for futility, but Bayesian calibration of such designs is usually based on comput…
stat.ME2026
Power and Sample Size Calculations for Bayes Factors in two-arm clinical Phase II Trials with binary Endpoints
Riko Kelter
Bayesian sample size calculations in clinical trials usually rely on complex Monte Carlo simulations in practice. Obtaining bounds on Bayesian notions of the false-positive rate an…