72 citations · 149 across the 5 of their papers we have counts for
3 papers · 1 filter
Metabolically Stable Neurotensin Analogs Exert Potent and Long-Acting Analgesia Without Hypothermia
Mélanie Vivancos, Roberto Fanelli, Élie Besserer-Offroy +9
The endogenous tridecapeptide neurotensin (NT) has emerged as an important inhibitory modulator of pain transmission, exerting its analgesic action through the activation of the G…
Pain relief devoid of opioid side effects following central action of a silylated neurotensin analog
Pascal Tétreault, Élie Besserer-Offroy, Rebecca L. Brouillette +12
Neurotensin (NT) exerts naloxone-insensitive antinociceptive action through its binding to both NTS1 and NTS2 receptors and NT analogs provide stronger pain relief than morphine on…
Cell-penetrating pepducins targeting the neurotensin receptor type 1 relieve pain
Rebecca L. Brouillette, Élie Besserer-Offroy, Christine E. Mona +8
Pepducins are cell-penetrating, membrane-tethered lipopeptides designed to target the intracellular region of a G protein-coupled receptor (GPCR) in order to allosterically modulat…