134 citations · 148 across the 9 of their papers we have counts for
3 papers · 1 filter
Evaluating and improving real-world evidence with Targeted Learning
Susan Gruber, Rachael V. Phillips, Hana Lee +2
Purpose: The Targeted Learning roadmap provides a systematic guide for generating and evaluating real-world evidence (RWE). From a regulatory perspective, RWE arises from diverse s…
Targeted learning: Towards a future informed by real-world evidence
Susan Gruber, Rachael V. Phillips, Hana Lee +3
The 21st Century Cures Act of 2016 includes a provision for the U.S. Food and Drug Administration (FDA) to evaluate the potential use of real-world evidence (RWE) to support new in…
Practical considerations for specifying a super learner
Rachael V. Phillips, Mark J. van der Laan, Hana Lee +1
Common tasks encountered in epidemiology, including disease incidence estimation and causal inference, rely on predictive modeling. Constructing a predictive model can be thought o…