activity
20172026
most citedNon-parametric efficient causal mediation with intermediate confounders

59 citations · 109 across the 16 of their papers we have counts for

collaborators

16 papers

stat.ME2026

From Subgroups to Population Composition: A Transportability Approach to Effect Heterogeneity

Michael Cheung, Candus Shi, Kara E Rudolph +3

Identifying heterogeneous populations across which exposure effects vary is essential for transportability applications, cost-benefit analyses, and intervention prioritization. Tra…

stat.ME2023★ 11 cited

Studying continuous, time-varying, and/or complex exposures using longitudinal modified treatment policies

Katherine L. Hoffman, Diego Salazar-Barreto, Nicholas Williams +2

This tutorial discusses methodology for causal inference using longitudinal modified treatment policies. This method facilitates the mathematical formalization, identification, and…

stat.ME2023★ 2 cited

Improving efficiency in transporting average treatment effects

Kara E. Rudolph, Nicholas T. Williams, Elizabeth A. Stuart +1

We develop flexible, semiparametric estimators of the average treatment effect (ATE) transported to a new population ("target population") that offer potential efficiency gains. Tr…

stat.ME2022

All models are wrong, but which are useful? Comparing parametric and nonparametric estimation of causal effects in finite samples

Kara E. Rudolph, Nicholas Williams, Caleb H. Miles +2

There is a long-standing debate in the statistical, epidemiological and econometric fields as to whether nonparametric estimation that uses data-adaptive methods, like machine lear…

stat.ME2022★ 2 cited

Nonparametric estimators of interventional (transported) direct and indirect effects that accommodate multiple mediators and multiple intermediate confounders

Kara E Rudolph, Nicholas Williams, Ivan Diaz

Mediation analysis is appealing for its ability to improve understanding of the mechanistic drivers of causal effects, but real-world data complexities challenge its successful imp…

stat.ME2022

A novel decomposition to explain heterogeneity in observational and randomized studies of causality

Brian Gilbert, Ivan Dıaz, Kara E. Rudolph +2

This paper introduces a novel decomposition framework to explain heterogeneity in causal effects observed across different studies, considering both observational and randomized se…

stat.ME2022

Efficient and flexible estimation of natural mediation effects under intermediate confounding and monotonicity constraints

Kara E. Rudolph, Ivan Diaz

Natural direct and indirect effects are mediational estimands that decompose the average treatment effect and describe how outcomes would be affected by contrasting levels of a tre…

stat.ME2021★ 1 cited

Causal mediation with instrumental variables

Kara E. Rudolph, Nicholas Williams, Ivan Diaz

Mediation analysis is a strategy for understanding the mechanisms by which treatments or interventions affect later outcomes. Mediation analysis is frequently applied in randomized…

stat.AP2021

When effects cannot be estimated: redefining estimands to understand the effects of naloxone access laws

Kara E. Rudolph, Catherine Gimbrone, Ellicott C. Matthay +4

Violations of the positivity assumption (also called the common support condition) challenge health policy research, and can result in significant bias, large variance, and invalid…

stat.AP2021

When the ends don't justify the means: Learning a treatment strategy to prevent harmful indirect effects

Kara E. Rudolph, Ivan Diaz

There is a growing literature on finding so-called optimal treatment rules, which are rules by which to assign treatment to individuals based on an individual's characteristics, su…

stat.ME2020

Nonparametric causal mediation analysis for stochastic interventional (in)direct effects

Nima S. Hejazi, Kara E. Rudolph, Mark J. van der Laan +1

Causal mediation analysis has historically been limited in two important ways: (i) a focus has traditionally been placed on binary treatments and static interventions, and (ii) dir…

stat.ME2020

Efficiently transporting causal (in)direct effects to new populations under intermediate confounding and with multiple mediators

Kara E. Rudolph, Ivan Diaz

The same intervention can produce different effects in different sites. Transport mediation estimators can estimate the extent to which such differences can be explained by differe…

stat.ME2019★ 59 cited

Non-parametric efficient causal mediation with intermediate confounders

Iván Díaz, Nima S. Hejazi, Kara E. Rudolph +1

Interventional effects for mediation analysis were proposed as a solution to the lack of identifiability of natural (in)direct effects in the presence of a mediator-outcome confoun…

stat.ME2019★ 11 cited

Transporting stochastic direct and indirect effects to new populations

Kara E Rudolph, Jonathan Levy, Mark J van der Laan

Transported mediation effects may contribute to understanding how and why interventions may work differently when applied to new populations. However, we are not aware of any estim…

stat.ME2018★ 7 cited

Complier stochastic direct effects: identification and robust estimation

Kara E Rudolph, Oleg Sofrygin, Mark J van der Laan

Mediation analysis is critical to understanding the mechanisms underlying exposure-outcome relationships. In this paper, we identify the instrumental variable (IV)-direct effect of…

stat.AP2017★ 16 cited

Robust and Flexible Estimation of Stochastic Mediation Effects: A Proposed Method and Example in a Randomized Trial Setting

Kara E. Rudolph, Oleg Sofrygin, Wenjing Zheng +1

Causal mediation analysis can improve understanding of the mechanisms underlying epidemiologic associations. However, the utility of natural direct and indirect effect estimation h…