activity
20172022
most citedScale-invariant biomarker discovery in urine and plasma metabolite fingerprints

18 citations · 23 across the 6 of their papers we have counts for

collaborators

7 papers

stat.ME2022★ 4 cited

BITES: Balanced Individual Treatment Effect for Survival data

Stefan Schrod, Andreas Schäfer, Stefan Solbrig +7

Estimating the effects of interventions on patient outcome is one of the key aspects of personalized medicine. Their inference is often challenged by the fact that the training dat…

stat.ML2021

Differentiated uniformization: A new method for inferring Markov chains on combinatorial state spaces including stochastic epidemic models

Kevin Rupp, Rudolf Schill, Jonas Süskind +6

Motivation: We consider continuous-time Markov chains that describe the stochastic evolution of a dynamical system by a transition-rate matrix which depends on a parameter .…

math.NA2020

Low-rank tensor methods for Markov chains with applications to tumor progression models

Peter Georg, Lars Grasedyck, Maren Klever +3

Continuous-time Markov chains describing interacting processes exhibit a state space that grows exponentially in the number of processes. This state-space explosion renders the com…

q-bio.QM2020

Lyra -- containerized microservices for browsing shared biomedical data

Michael Huttner, Claudio Lottaz, Christian Kohler +1

Research papers in the biomedical field come with large and complex data sets that are shared with the scientific community as unstructured data files via public data repositories.…

stat.AP2018

Fully integrative data analysis of NMR metabolic fingerprints with comprehensive patient data: a case report based on the German Chronic Kidney Disease (GCKD) study

Helena U. Zacharias, Michael Altenbuchinger, Stefan Solbrig +11

Omics data facilitate the gain of novel insights into the pathophysiology of diseases and, consequently, their diagnosis, treatment, and prevention. To that end, it is necessary to…

q-bio.QM2018★ 1 cited

Loss-function learning for digital tissue deconvolution

Franziska Görtler, Stefan Solbrig, Tilo Wettig +3

The gene expression profile of a tissue averages the expression profiles of all cells in this tissue. Digital tissue deconvolution (DTD) addresses the following inverse problem: Gi…