38 citations · 101 across the 7 of their papers we have counts for
7 papers
Ensemble inversion for brain tumor growth models with mass effect
Shashank Subramanian, Klaudius Scheufele, Naveen Himthani +2
We propose a method for extracting physics-based biomarkers from a single multiparametric Magnetic Resonance Imaging (mpMRI) scan bearing a glioma tumor. We account for mass effect…
Calibration of Biophysical Models for tau-Protein Spreading in Alzheimer's Disease from PET-MRI
Klaudius Scheufele, Shashank Subramanian, George Biros
Aggregates of misfolded tau proteins (or just 'tau' for brevity) play a crucial role in the progression of Alzheimer's disease (AD) as they correlate with cell death and accelerate…
Multiatlas Calibration of Biophysical Brain Tumor Growth Models with Mass Effect
Shashank Subramanian, Klaudius Scheufele, Naveen Himthani +1
We present a 3D fully-automatic method for the calibration of partial differential equation (PDE) models of glioblastoma (GBM) growth with mass effect, the deformation of brain tis…
Automatic MRI-Driven Model Calibration for Advanced Brain Tumor Progression Analysis
Klaudius Scheufele, Shashank Subramanian, George Biros
Our objective is the calibration of mathematical tumor growth models from a single multiparametric scan. The target problem is the analysis of preoperative Glioblastoma (GBM) scans…
Image-Driven Biophysical Tumor Growth Model Calibration
Klaudius Scheufele, Shashank Subramanian, Andreas Mang +2
We present a novel formulation for the calibration of a biophysical tumor growth model from a single-time snapshot, MRI scan of a glioblastoma patient. Tumor growth models are typi…
Where did the tumor start? An inverse solver with sparse localization for tumor growth models
Shashank Subramanian, Klaudius Scheufele, Miriam Mehl +1
We present a numerical scheme for solving an inverse problem for parameter estimation in tumor growth models for glioblastomas, a form of aggressive primary brain tumor. The growth…