455 citations · 711 across the 25 of their papers we have counts for
4 papers · 1 filter
Calibration of Biophysical Models for tau-Protein Spreading in Alzheimer's Disease from PET-MRI
Klaudius Scheufele, Shashank Subramanian, George Biros
Aggregates of misfolded tau proteins (or just 'tau' for brevity) play a crucial role in the progression of Alzheimer's disease (AD) as they correlate with cell death and accelerate…
Multiatlas Calibration of Biophysical Brain Tumor Growth Models with Mass Effect
Shashank Subramanian, Klaudius Scheufele, Naveen Himthani +1
We present a 3D fully-automatic method for the calibration of partial differential equation (PDE) models of glioblastoma (GBM) growth with mass effect, the deformation of brain tis…
Integrated Biophysical Modeling and Image Analysis: Application to Neuro-Oncology
Andreas Mang, Spyridon Bakas, Shashank Subramanian +2
Central nervous system (CNS) tumors come with the vastly heterogeneous histologic, molecular and radiographic landscape, rendering their precise characterization challenging. The r…
Automatic MRI-Driven Model Calibration for Advanced Brain Tumor Progression Analysis
Klaudius Scheufele, Shashank Subramanian, George Biros
Our objective is the calibration of mathematical tumor growth models from a single multiparametric scan. The target problem is the analysis of preoperative Glioblastoma (GBM) scans…