185 citations · 360 across the 11 of their papers we have counts for
13 papers
Emission-associated energy deposition and Cherenkov-dose proportionality in megavoltage photon beams
Xianghuan He, Yao Hao, Changyu Sun +4
Background: Quantitative Cherenkov-to-dose conversion depends on beam spectrum, field size, depth, and material properties. Purpose: To distinguish dose contributions with and with…
Design and Characterization of a Novel Scintillator Array for In Vivo Monitoring During UHDR PBS Proton Therapy
Roman Vasyltsiv, Joseph Harms, Megan Clark +4
Background: Ultra-high dose rate proton therapy shows promise in tissue sparing by enhancing therapeutic ratio through the FLASH effect. In radiotherapy, accurate in vivo dosimetry…
Robust Real-time Segmentation of Bio-Morphological Features in Human Cherenkov Imaging during Radiotherapy via Deep Learning
Shiru Wang, Yao Chen, Lesley A. Jarvis +6
Cherenkov imaging enables real-time visualization of megavoltage X-ray or electron beam delivery to the patient during Radiation Therapy (RT). Bio-morphological features, such as v…
Cherenkov Imaged Bio-morphological Features Verify Patient Positioning with Deformable Tissue Translocation in Breast Radiotherapy
Yao Chen, Savannah M. Decker, Petr Bruza +5
Accurate patient positioning is critical for precise radiotherapy dose delivery, as positioning errors can significantly affect treatment outcomes. This study introduces a novel me…
Quantitative real-time measurements of dose and dose rate in UHDR proton pencil beams via scintillation imaging system
Megan Clark, Joseph Harms, Roman Vasyltsiv +6
Purpose: Ultra-fast scintillation imaging has been shown to provide a unique tool for spatio-temporal dosimetry of conventional cyclotron and synchrocyclotron pencil beam scanning…
Comparing fast imaging techniques for individual pulse imaging by Cherenkov in vivo from electron FLASH irradiation
Mahbubur Rahman, M. Ramish Ashraf, Rongxiao Zhang +6
Objective: In this study, a fast imaging technique was developed for the first in vivo Cherenkov emission imaging from an ultra-high dose rate (UHDR) electron beam source at single…
Characterization of a Diode Dosimeter for UHDR FLASH Radiotherapy
Mahbubur Rahman, Jakub Kozelka, Jeff Hildreth +8
Purpose: A diode EDGE Detector with a newly designed electrometer has been characterized for use in an UHDR electron beam and demonstrated appropriateness for UHDR FLASH radiothera…
Failure Mode and Effects Analysis (FMEA) for Experimental Use of FLASH on a Clinical Accelerator
Mahbubur Rahman, Rongxiao Zhang, David J. Gladstone +6
Background: Use of a linear accelerator in ultra-high dose rate (UHDR) mode can provide a conduit for wider access to UHDR FLASH effects, sparing normal tissue, but care needs to b…
Individual Pulse Monitoring and Dose Control System for Pre-Clinical Implementation of FLASH-RT
M. Ramish Ashraf, Mahbubur Rahman, Xu Cao +7
Ultra-high dose rate electron sources require dose rate independent dosimeters and a calibrated dose control system for accurate delivery. In this study, we developed a single-puls…
Retrospective Evaluation of an Always-on Cherenkov Imaging System for Radiotherapy Quality Improvement
Daniel A. Alexander, Michael Jermyn, Petr Bruza +11
Purpose: Cherenkov imaging is now clinically available to track the course of radiation therapy as a treatment verification tool. The aim of this work was to discover the benefits…
Treatment Planning System for Electron FLASH Radiotherapy: Open-source for Clinical Implementation
Mahbubur Rahman, M. Ramish Ashraf, David J. Gladstone +7
Purpose: A Monte Carlo (MC) beam model and its implementation in a clinical treatment planning system (TPS, Varian Eclipse) are presented for a modified ultra-high dose-rate electr…
Electron FLASH Delivery at Treatment Room Isocenter for Efficient Reversible Conversion of a Clinical LINAC
Mahbubur Rahman, M. Ramish Ashraf, Rongxiao Zhang +8
Purpose: In this study, procedures were developed to achieve efficient reversible conversion of a clinical linear accelerator (LINAC) and deliver electron FLASH (eFLASH) or convent…
Dosimetry for FLASH Radiotherapy: A Review of Tools and the Role of Radioluminescence and Cherenkov Emission
Muhammad Ramish Ashraf, Mahbubur Rahman, Rongxiao Zhang +4
While spatial dose conformity delivered to a target volume has been pushed to its practical limits with advanced treatment planning and delivery, investigations in novel temporal d…