6 citations · 8 across the 5 of their papers we have counts for
5 papers
GlycoMAC: A Multiscale Metabolic-Glycosylation Framework for Predicting Glycosylation Across Conditions in Mammalian Cell Cultures
Yuming Zeng, Sarah W. Harcum, Jinxiang Pei +1
Antibody productivity and glycosylation quality in CHO cell cultures emerge from a dynamically evolving metabolic environment, yet existing models often work in isolation or at a s…
A Modular Mechanistic In Silico Model for In Vitro Transcription Process Yield and Product Quality Prediction
Keqi Wang, Keilung Choy, Eli Reiser +10
In vitro transcription (IVT) plays a critical role in the manufacture of mRNA vaccines and therapeutics. Optimizing mRNA yield and ensuring product quality, such as capping efficie…
Stochastic Biological System-of-Systems Modelling for iPSC Culture
Hua Zheng, Sarah W. Harcum, Jinxiang Pei +1
Large-scale manufacturing of induced pluripotent stem cells (iPSCs) is essential for cell therapies and regenerative medicines. Yet, iPSCs form large cell aggregates in suspension…
Blockchain-Enabled Internet-of-Things Platform for End-to-End Industrial Hemp Supply Chain
Keqi Wang, Wei Xie, Wencen Wu +2
After being legalized as an agricultural commodity by the 2018 U.S. Farm Bill, the Industrial Hemp production is moved from limited pilot programs to a regulated agriculture produc…
Simulation-Based Digital Twin Development for Blockchain Enabled End-to-End Industrial Hemp Supply Chain Risk Management
Keqi Wang, Wei Xie, Wencen Wu +4
With the passage of the 2018 U.S. Farm Bill, Industrial Hemp production is moved from limited pilot programs to a regulated agriculture production system. However, Industrial Hemp…