From the 1 of 3 linked papers with an AI index.
3 papers
Factorial clinical trials in the presence and absence of plausible statistical interactions between treatment factors. A historical review of the methodological literature
Rebecca E. A. Walwyn, Pritaporn Kingkaew, Alan A. Montgomery +2
The paper reviews the methodological literature on factorial clinical trials, contrasting guidance for when statistical interactions between treatment factors are expected versus n…
Sample size calculations for multilevel factorial longitudinal cluster randomised trials
Rhys Bowden, Rebecca Walwyn, Jessica Kasza +4
Typically, trials investigate the impact of either an individual-level intervention on participant outcomes, or the impact of a cluster-level intervention on participant outcomes.…
Orthogonal factorial designs for trials of therapist-delivered interventions: Randomising intervention-therapist combinations to patients
Rebecca EA Walwyn, Rosemary A Bailey, Arpan Singh +2
It is recognised that treatment-related clustering should be allowed for in the sample size and analyses of individually-randomised parallel-group trials that evaluate therapist-de…