activity
20202023
most citedFibration symmetries uncover the building blocks of biological networks

48 citations · 121 across the 8 of their papers we have counts for

collaborators

8 papers

q-bio.CB2023

Complexity reduction by symmetry: uncovering the minimal regulatory network for logical computation in bacteria

Luis A. Álvarez-García, Wolfram Liebermeister, Ian Leifer +1

Symmetry principles play an important role in geometry, and physics, allowing for the reduction of complicated systems to simpler, more comprehensible models that preserve the syst…

q-bio.QM2021★ 5 cited

Quasifibrations of Graphs to Find Symmetries in Biological Networks

Paolo Boldi, Ian Leifer, Hernán A. Makse

A fibration of graphs is an homomorphism that is a local isomorphism of in-neighbourhoods, much in the same way a covering projection is a local isomorphism of neighbourhoods. Rece…

q-bio.QM2021★ 7 cited

Symmetry-driven network reconstruction through pseudobalanced coloring optimization

Ian Leifer, David Phillips, Francesco Sorrentino +1

Symmetries found through automorphisms or graph fibrations provide important insights in network analysis. Symmetries identify clusters of robust synchronization in the network whi…

eess.SY2021★ 17 cited

Matryoshka and Disjoint Cluster Synchronization of Networks

Amirhossein Nazerian, Shirin Panahi, Ian Leifer +3

The main motivation for this paper is to present a definition of network synchronizability for the case of cluster synchronization (CS), in an analogous fashion to Barahona and Pec…

q-bio.MN2021★ 7 cited

Fast algorithm to identify cluster synchrony through fibration symmetries in large information-processing networks

Higor S. Monteiro, Ian Leifer, Saulo D. S. Reis +2

Recent studies revealed an important interplay between the detailed structure of fibration symmetric circuits and the functionality of biological and non-biological networks within…

q-bio.MN2021★ 14 cited

Predicting synchronized gene coexpression patterns from fibration symmetries in gene regulatory networks in bacteria

Ian Leifer, Mishael Sánchez-Pérez, Cecilia Ishida +1

Background: Gene regulatory networks coordinate the expression of genes across physiological states and ensure a synchronized expression of genes in cellular subsystems, critical f…

q-bio.GN2020★ 23 cited

Circuits with broken fibration symmetries perform core logic computations in biological networks

Ian Leifer, Flaviano Morone, Saulo D. S. Reis +3

We show that logic computational circuits in gene regulatory networks arise from a fibration symmetry breaking in the network structure. From this idea we implement a constructive…

q-bio.MN2020★ 48 cited

Fibration symmetries uncover the building blocks of biological networks

Flaviano Morone, Ian Leifer, Hernan A. Makse

A major ambition of systems science is to uncover the building blocks of any biological network to decipher how cellular function emerges from their interactions. Here, we introduc…