4 citations · 4 across the 3 of their papers we have counts for
5 papers
A protocol for dynamic model calibration
Alejandro F. Villaverde, Dilan Pathirana, Fabian Fröhlich +2
Ordinary differential equation models are nowadays widely used for the mechanistic description of biological processes and their temporal evolution. These models typically have man…
Repairing dynamic models: a method to obtain identifiable and observable reparameterizations with mechanistic insights
Gemma Massonis, Julio R. Banga, Alejandro F. Villaverde
Mechanistic dynamic models allow for a quantitative and systematic interpretation of data and the generation of testable hypotheses. However, these models are often over-parameteri…
Structural Identifiability and Observability of Compartmental Models of the COVID-19 Pandemic
Gemma Massonis, Julio R. Banga, Alejandro F. Villaverde
The recent coronavirus disease (COVID-19) outbreak has dramatically increased the public awareness and appreciation of the utility of dynamic models. At the same time, the dissemin…
Nonlinear observability algorithms with known and unknown inputs: analysis and implementation
Nerea Martínez, Alejandro F. Villaverde
The observability of a dynamical system is affected by the presence of external inputs, either known (such as control actions) or unknown (disturbances). Inputs of unknown magnitud…
Observability and Structural Identifiability of Nonlinear Biological Systems
Alejandro F. Villaverde
Observability is a modelling property that describes the possibility of inferring the internal state of a system from observations of its output. A related property, structural ide…