activity
20182026
most citedPrecise tracking of vaccine-responding T-cell clones reveals convergent and personalized response in identical twins

145 citations · 230 across the 13 of their papers we have counts for

collaborators

14 papers

physics.soc-ph2026

Role differentiation as ignition of a collective information engine: Structuration in Agent Populations

Maximilian Puelma Touzel

Informational active matter shows how measurement-informed decisions produce collective order, so far in systems that reach consensus. We design collective information engines stru…

cs.AI2026

Position: Collusion Risks Among AI Reasoning Agents Justify Certification Requirements for Making Market Decisions

Matthew Riemer, Tommaso Tosato, Amin Memarian +4

This position paper argues that AI agents with chain-of-thought reasoning capabilities are predisposed to exhibit collusive behavior and should be required to obtain behavioral cer…

cs.MA2026

EASE Configuration Facilitates A Reproducible Science of LLM Social Simulations

Sneheel Sarangi, Maximilian Puelma Touzel, Aurélien Bück-Kaeffer +3

LLMs are increasingly deployed to simulate social interactions, yet many of the existing simulators remain ad hoc and monolithic. This lack of architectural standardization prevent…

cs.GT2026

The fitness landscape of social norms in social dilemmas

Maximilian Puelma Touzel

By specifying behaviour across multiple agents, social norms are a coordination approach to resolving social dilemmas. Decentralized and wide adoption can be achieved by norms whos…

cs.MA2026

The Cookbook: Design Space of LLM-based Social Simulations

Aurélien Bück-Kaeffer, Sneheel Sarangi, Maximilian Puelma Touzel +3

Studies attempting to simulate human behavior with grow in numbers while LLM-only social networks have started appearing outside of controlled settings…

cs.CL2025

: A Social Media User Dataset for LLM Persona Evaluation and Training

Aurélien Bück-Kaeffer, Je Qin Chooi, Dan Zhao +5

Large language models (LLMs) offer promising capabilities for simulating social media dynamics at scale, enabling studies that would be ethically or logistically challenging with h…

cs.CL2025

Veracity: An Open-Source AI Fact-Checking System

Taylor Lynn Curtis, Maximilian Puelma Touzel, William Garneau +8

The proliferation of misinformation poses a significant threat to society, exacerbated by the capabilities of generative AI. This demo paper introduces Veracity, an open-source AI…

cs.SI2024

A Simulation System Towards Solving Societal-Scale Manipulation

Maximilian Puelma Touzel, Sneheel Sarangi, Austin Welch +12

The rise of AI-driven manipulation poses significant risks to societal trust and democratic processes. Yet, studying these effects in real-world settings at scale is ethically and…

cs.LG2021★ 2 cited

Continual Learning In Environments With Polynomial Mixing Times

Matthew Riemer, Sharath Chandra Raparthy, Ignacio Cases +3

The mixing time of the Markov chain induced by a policy limits performance in real-world continual learning scenarios. Yet, the effect of mixing times on learning in continual rein…

q-bio.GN2021★ 1 cited

NoisET: Noise learning and Expansion detection of T-cell receptors

Meriem Bensouda Koraichi, Maximilian Puelma Touzel, Andrea Mazzolini +2

High-throughput sequencing of T- and B-cell receptors makes it possible to track immune repertoires across time, in different tissues, in acute and chronic diseases and in healthy…

cs.LG2020★ 3 cited

On Lyapunov Exponents for RNNs: Understanding Information Propagation Using Dynamical Systems Tools

Ryan Vogt, Maximilian Puelma Touzel, Eli Shlizerman +1

Recurrent neural networks (RNNs) have been successfully applied to a variety of problems involving sequential data, but their optimization is sensitive to parameter initialization,…

q-bio.QM2019★ 60 cited

Inferring the immune response from repertoire sequencing

Maximilian Puelma Touzel, Aleksandra M. Walczak, Thierry Mora

High-throughput sequencing of B- and T-cell receptors makes it possible to track immune repertoires across time, in different tissues, and in acute and chronic diseases or in healt…

cs.LG2019★ 19 cited

Non-normal Recurrent Neural Network (nnRNN): learning long time dependencies while improving expressivity with transient dynamics

Giancarlo Kerg, Kyle Goyette, Maximilian Puelma Touzel +4

A recent strategy to circumvent the exploding and vanishing gradient problem in RNNs, and to allow the stable propagation of signals over long time scales, is to constrain recurren…

q-bio.PE2018★ 145 cited

Precise tracking of vaccine-responding T-cell clones reveals convergent and personalized response in identical twins

Mikhail V. Pogorelyy, Anastasia A. Minervina, Maximilian Puelma Touzel +11

T-cell receptor (TCR) repertoire data contain information about infections that could be used in disease diagnostics and vaccine development, but extracting that information remain…