activity
20202026
most citedA Deep Learning-Based Method for Automatic Segmentation of Proximal Femur from Quantitative Computed Tomography Images

7 citations · 16 across the 8 of their papers we have counts for

collaborators

10 papers

q-bio.QM2026

DXA-Derived Skeletal Phenotypes and Hip Fracture Risk: A Backdoor-Adjusted Causal Analysis

Zixin Shi, Chen Zhao, Meiling Zhou +8

Purpose: To compare dual-energy X-ray absorptiometry (DXA)-derived hip skeletal phenotypes in relation to hip fracture risk using prespecified confounder adjustment and to assess w…

cs.LG2026

Improving Generalizability of Hip Fracture Risk Prediction via Domain Adaptation Across Multiple Cohorts

Shuo Sun, Meiling Zhou, Chen Zhao +8

Clinical risk prediction models often fail to be generalized across cohorts because underlying data distributions differ by clinical site, region, demographics, and measurement pro…

cs.CV2025

PF-DAformer: Proximal Femur Segmentation via Domain Adaptive Transformer for Dual-Center QCT

Rochak Dhakal, Chen Zhao, Zixin Shi +6

Quantitative computed tomography (QCT) plays a crucial role in assessing bone strength and fracture risk by enabling volumetric analysis of bone density distribution in the proxima…

cs.LG2025

An Advanced Two-Stage Model with High Sensitivity and Generalizability for Prediction of Hip Fracture Risk Using Multiple Datasets

Shuo Sun, Meiling Zhou, Chen Zhao +8

Hip fractures are a major cause of disability, mortality, and healthcare burden in older adults, underscoring the need for early risk assessment. However, commonly used tools such…

cs.CV2025★ 1 cited

ICGM-FRAX: Iterative Cross Graph Matching for Hip Fracture Risk Assessment using Dual-energy X-ray Absorptiometry Images

Chen Zhao, Anjum Shaik, Joyce H. Keyak +7

Hip fractures represent a major health concern, particularly among the elderly, often leading decreased mobility and increased mortality. Early and accurate detection of at risk in…

physics.med-ph2024

A Staged Approach using Machine Learning and Uncertainty Quantification to Predict the Risk of Hip Fracture

Anjum Shaik, Kristoffer Larsen, Nancy E. Lane +8

Despite advancements in medical care, hip fractures impose a significant burden on individuals and healthcare systems. This paper focuses on the prediction of hip fracture risk in…

cs.LG2023

A new method of modeling the multi-stage decision-making process of CRT using machine learning with uncertainty quantification

Kristoffer Larsen, Chen Zhao, Joyce Keyak +7

Aims. The purpose of this study is to create a multi-stage machine learning model to predict cardiac resynchronization therapy (CRT) response for heart failure (HF) patients. This…

cs.LG2022★ 1 cited

A New Hip Fracture Risk Index Derived from FEA-Computed Proximal Femur Fracture Loads and Energies-to-Failure

Xuewei Cao, Joyce H Keyak, Sigurdur Sigurdsson +7

Hip fracture risk assessment is an important but challenging task. Quantitative CT-based patient specific finite element analysis (FEA) computes the force (fracture load) to break…

cs.LG2022★ 7 cited

Multi-view information fusion using multi-view variational autoencoders to predict proximal femoral strength

Chen Zhao, Joyce H Keyak, Xuewei Cao +10

The aim of this paper is to design a deep learning-based model to predict proximal femoral strength using multi-view information fusion. Method: We developed new models using multi…

physics.med-ph2020★ 7 cited

A Deep Learning-Based Method for Automatic Segmentation of Proximal Femur from Quantitative Computed Tomography Images

Chen Zhao, Joyce H. Keyak, Jinshan Tang +10

Purpose: Proximal femur image analyses based on quantitative computed tomography (QCT) provide a method to quantify the bone density and evaluate osteoporosis and risk of fracture.…